Anti-L1CAM [UJ181.4]
Invented by Dr JOHN KEMSHEAD from SHIRE PHARMACEUTICALS
Invented at Institute Of Child Health
- Datasheet
- References (7)
- Inventor Info
Info
| Catalogue Number | 151179 |
| Applications | IHC IP WB |
| Antigen/Gene or Protein Targets | L1 cell adhesion molecule (L1CAM; CD171) |
| Reactivity | Human |
| Relevance | Used in diagnosis of primitive neuroectodermal tumours. Binds to tumours of neural and glial origin and does not bind to paediatric or adult brain. Used for bone marrow purging and intrathecal targeting |
| Host | Mouse |
| Immunogen | 16 week human foetal brain. |
| Subclass | IgG1 |
| Molecular Weight (kDa) | 220-240 |
| Myeloma Used | P3X63Ag8.653 |
| Recommended Growing Conditions | RPMI 1640 or DMEM + 5% FCS, |
| Strain | Balb/c |
| Research Area | Adhesion, Cell Signaling & Signal Transduction, Neurobiology |
References: 7 entries
Garson.JA. 1983. MD Thesis. Birmingham
Bourne et al. 1989. Hybridoma. 8(4):415-26. PMID: 2550359.
Monoclonal antibodies M340 and UJ181.4 recognize antigens associated with primitive neuroectodermal tumours/tissues.
Europe PMC ID: 2550359
Coakham et al. 1985. J Clin Pathol. 38(2):165-73. PMID: 3881481.
Immunohistological diagnosis of central nervous system tumours using a monoclonal antibody panel.
Europe PMC ID: 3881481
Kemshead et al. 1983. Int J Cancer. 31(2):187-95. PMID: 6826247.
Monoclonal antibody UJ 127:11 detects a 220,000-240,000 kdal. glycoprotein present on a sub-set of neuroectodermally derived cells.
Europe PMC ID: 6826247
Add a reference
References: 7 entries
Garson.JA. 1983. MD Thesis. Birmingham
Bourne et al. 1989. Hybridoma. 8(4):415-26. PMID: 2550359.
Monoclonal antibodies M340 and UJ181.4 recognize antigens associated with primitive neuroectodermal tumours/tissues.
Coakham et al. 1985. J Clin Pathol. 38(2):165-73. PMID: 3881481.
Immunohistological diagnosis of central nervous system tumours using a monoclonal antibody panel.
Kemshead et al. 1983. Int J Cancer. 31(2):187-95. PMID: 6826247.
Monoclonal antibody UJ 127:11 detects a 220,000-240,000 kdal. glycoprotein present on a sub-set of neuroectodermally derived cells.
Add a reference
