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Anti-L1CAM [UJ181.4]

Invented by Dr JOHN KEMSHEAD at SHIRE PHARMACEUTICALS

Info

Catalogue Number 151179
Applications IHC IP WB
Antigen/Gene or Protein Targets L1 cell adhesion molecule (L1CAM; CD171)
Reactivity Human
Relevance Used in diagnosis of primitive neuroectodermal tumours. Binds to tumours of neural and glial origin and does not bind to paediatric or adult brain. Used for bone marrow purging and intrathecal targeting
Host Mouse
Immunogen 16 week human foetal brain.
Subclass IgG1
Molecular Weight (kDa) 220-240
Myeloma Used P3X63Ag8.653
Recommended Growing Conditions RPMI 1640 or DMEM + 5% FCS,
Strain Balb/c
Research Area Adhesion, Cell Signaling & Signal Transduction, Neurobiology

References: 7 entries

Garson.JA. 1983. MD Thesis. Birmingham

Bourne et al. 1989. Hybridoma. 8(4):415-26. PMID: 2550359.

Monoclonal antibodies M340 and UJ181.4 recognize antigens associated with primitive neuroectodermal tumours/tissues.

Europe PMC ID: 2550359

Coakham et al. 1985. J Clin Pathol. 38(2):165-73. PMID: 3881481.

Immunohistological diagnosis of central nervous system tumours using a monoclonal antibody panel.

Europe PMC ID: 3881481

Kemshead et al. 1983. Int J Cancer. 31(2):187-95. PMID: 6826247.

Monoclonal antibody UJ 127:11 detects a 220,000-240,000 kdal. glycoprotein present on a sub-set of neuroectodermally derived cells.

Europe PMC ID: 6826247


Add a reference

References: 7 entries

Garson.JA. 1983. MD Thesis. Birmingham

Bourne et al. 1989. Hybridoma. 8(4):415-26. PMID: 2550359.

Monoclonal antibodies M340 and UJ181.4 recognize antigens associated with primitive neuroectodermal tumours/tissues.

Europe PMC ID: 2550359

Coakham et al. 1985. J Clin Pathol. 38(2):165-73. PMID: 3881481.

Immunohistological diagnosis of central nervous system tumours using a monoclonal antibody panel.

Europe PMC ID: 3881481

Kemshead et al. 1983. Int J Cancer. 31(2):187-95. PMID: 6826247.

Monoclonal antibody UJ 127:11 detects a 220,000-240,000 kdal. glycoprotein present on a sub-set of neuroectodermally derived cells.

Europe PMC ID: 6826247


Add a reference

References: 7 entries

Garson.JA. 1983. MD Thesis. Birmingham

Bourne et al. 1989. Hybridoma. 8(4):415-26. PMID: 2550359.

Monoclonal antibodies M340 and UJ181.4 recognize antigens associated with primitive neuroectodermal tumours/tissues.

Coakham et al. 1985. J Clin Pathol. 38(2):165-73. PMID: 3881481.

Immunohistological diagnosis of central nervous system tumours using a monoclonal antibody panel.

Kemshead et al. 1983. Int J Cancer. 31(2):187-95. PMID: 6826247.

Monoclonal antibody UJ 127:11 detects a 220,000-240,000 kdal. glycoprotein present on a sub-set of neuroectodermally derived cells.


Add a reference


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