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Anti-Leu1 [UCH-T2]


Catalogue Number 151176
Applications IHC IF WB
Antigen/Gene or Protein Targets Leu1 (CD5)
Synonyms CD5 Molecule 2; Lymphocyte Antigen T1/Leu-1; LEU1; CD5 Antigen; T1
Reactivity Human
Relevance Leu-1 is a surface glycoprotein present on peripheral T cells (>95%) and B-cell chronic lymphocytic leukaemia cells that binds CD72. Absence of the Leu-1 marker on childhood ALL cells is associated with a more favourable prognosis. UCH-T2 is useful for detection of T cells in peripheral blood and lymph nodes and categorisation of T cell lymphomas and B cell chronic lymphocytic leukaemia.
Host Mouse
Immunogen Thymocytes followed by Sezary T cells.
Subclass IgG1
Recommended Growing Conditions RPMI + 7.5% FCS
Strain Balb/c
Notes Recommended for Immunofluorescence and immunostaining of frozen samples and the enrichment of T cell populations by cell sorting or panning.
Research Area Immunology, Stem Cell Biology

References: 3 entries

Beverley PE & Callard RE. 1982. Protides Biol. Fluids. Colloq. 29:653-8.

Kap et al. 2009. J Histochem Cytochem. 57(12):1159-67. PMID: 19729671.

Gary-Gouy et al. 2007. J Immunol. 179(7):4335-44. PMID: 17878328.

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