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Anti-Fibrin [UC45]

Info

Catalogue Number 151172
Applications FACS IF IP RIA
Antigen/Gene or Protein Targets Fibrin alpha chain
Reactivity Human
Relevance Fibrin (also called Factor Ia) is a fibrous protein involved in the clotting of blood, and is non-globular. It is a fibrillar protein that is polymerised to form a "mesh" that forms a hemostatic plug or clot (in conjunction with platelets) over a wound site.
Host Mouse
Immunogen Human acute monoblastic leukemia cells.
Subclass IgM
Molecular Weight (kDa) 45
Myeloma Used P3/NS1/1-Ag4.1
Recommended Growing Conditions DMEM + 5% FCS
Strain Balb/c
Notes UC45 is specific for monocytic leukemias. The relevant antigens are not expressed in all cases with monocytic differentiation. Cross reacts with fibrinogen.
Research Area Cardiovascular

References: 4 entries

Wu et al. 2013. Am J Nucl Med Mol Imaging. 3(5):446-55. PMID: 24116353.

Linch et al. 1984. Blood. 63(3):566-73. PMID: 6365201.

Hogg et al. 1983. J Exp Med. 157(2):473-85. PMID: 6822786.

IF

Hogg et al. 1981. Cell. 24(3):875-84. PMID: 6788378.


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