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Anti-HPV16E7 [TVG 701Y]

Info

Catalogue Number 151170
Applications ELISA FACS IHC IF WB
Antigen/Gene or Protein Targets Human Papilloma Virus-16 early protein 7 (HPV16 E7)
Reactivity Human papilloma virus
Relevance The human papilloma virus (HPV) family of DNA tumor viruses includes HPV-16 and HPV-18, which are associated with a large proportion of cervical cancer cases. HPV early proteins E6 and E7 are the major viral oncoproteins that regulate cell proliferation through the inactivation of p53 and Rb1 tumour suppressor proteins respectively.
Host Mouse
Immunogen HPV 16 E7 synthesised from S. pombe
Subclass IgG2a
Molecular Weight (kDa) 57 (Please note - The molecular weight of the protein may vary due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.)
Myeloma Used P3/NS1/1-Ag4.1
Recommended Growing Conditions RPMI 1640 + 15% FCS.
Strain Balb/c
Research Area Cancer, Virology

References: 4 entries

Harris et al. 2013. Br J Cancer. 108(4):859-65. PMID: 23385729.

Combined treatment of the experimental human papilloma virus-16-positive cervical and head and neck cancers with cisplatin and radioimmunotherapy targeting viral E6 oncoprotein.

Europe PMC ID: 23385729

Tommasino et al. 1993. Oncogene. 8(1):195-202. PMID: 8380917.

HPV16 E7 protein associates with the protein kinase p33CDK2 and cyclin A.

Europe PMC ID: 8380917


Add a reference

References: 4 entries

Harris et al. 2013. Br J Cancer. 108(4):859-65. PMID: 23385729.

Combined treatment of the experimental human papilloma virus-16-positive cervical and head and neck cancers with cisplatin and radioimmunotherapy targeting viral E6 oncoprotein.

Europe PMC ID: 23385729

Tommasino et al. 1993. Oncogene. 8(1):195-202. PMID: 8380917.

HPV16 E7 protein associates with the protein kinase p33CDK2 and cyclin A.

Europe PMC ID: 8380917


Add a reference

References: 4 entries

Harris et al. 2013. Br J Cancer. 108(4):859-65. PMID: 23385729.

Combined treatment of the experimental human papilloma virus-16-positive cervical and head and neck cancers with cisplatin and radioimmunotherapy targeting viral E6 oncoprotein.

Tommasino et al. 1993. Oncogene. 8(1):195-202. PMID: 8380917.

HPV16 E7 protein associates with the protein kinase p33CDK2 and cyclin A.


Add a reference


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