Anti-HPV16E2 [TVG 261]
Invented at University of Cambridge
- Datasheet
- References (8)
- Inventor Info
Info
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| Catalogue Number | 151167 |
| Applications | ELISA IF IP WB |
| Antigen/Gene or Protein Targets | Human Papilloma virus-16 early protein 2 (HPV16 E2) |
| Reactivity | Human papilloma virus |
| Relevance | The human papilloma virus (HPV) family of DNA tumor viruses includes HPV-16 and HPV-18, which are associated with a large proportion of cervical cancer cases. E1 and E2 are proteins involved in the regulation of viral DNA replication. TVG 261 is useful for detection of protein in cervical lesions. |
| Host | Mouse |
| Immunogen | Vaccinia-E2 followed by intravenous injection of the maltose binding protein MBP-E2 (generated from an expression vector in which the E2 ORF was cloned in frame with malE). |
| Subclass | IgG1 |
| Myeloma Used | P3/NS1/1-Ag4.1 |
| Recommended Growing Conditions | DMEM + 5% FCS |
| Strain | Balb/c |
| Research Area | Cancer, Virology |
References: 8 entries
Evans et al. 2019. J Virol. 93(4):. PMID: 30518656.
WB
Ludwig et al. 2018. Front Oncol. 8:445. PMID: 30370252.
WB
Evans et al. 2017. Oncotarget. 8(47):81892-81909. PMID: 29137231.
IF WB
Campos-León et al. 2017. J Virol. 91(5):. PMID: 28031358.
IP WB
A deletion in the gene encoding the CD45 antigen in a patient with SCID.
Europe PMC ID: 11145714
A point mutation within CD45 exon A is the cause of variant CD45RA splicing in humans.
Europe PMC ID: 9485182
Hibma et al. 1995. Eur J Biochem. 229(2):517-25. PMID: 7744075.
WB
The interaction between human papillomavirus type 16 E1 and E2 proteins is blocked by an antibody to the N-terminal region of E2.
Europe PMC ID: 7744075
Add a reference
References: 8 entries
Evans et al. 2019. J Virol. 93(4):. PMID: 30518656.
WB
Ludwig et al. 2018. Front Oncol. 8:445. PMID: 30370252.
WB
Evans et al. 2017. Oncotarget. 8(47):81892-81909. PMID: 29137231.
IF WB
Campos-León et al. 2017. J Virol. 91(5):. PMID: 28031358.
IP WB
A deletion in the gene encoding the CD45 antigen in a patient with SCID.
A point mutation within CD45 exon A is the cause of variant CD45RA splicing in humans.
Hibma et al. 1995. Eur J Biochem. 229(2):517-25. PMID: 7744075.
WB
The interaction between human papillomavirus type 16 E1 and E2 proteins is blocked by an antibody to the N-terminal region of E2.
Add a reference
