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Anti-HPV16E2 [TVG 261]

Info

Catalogue Number 151167
Applications ELISA WB
Antigen/Gene or Protein Targets Human Papilloma virus-16 early protein 2 (HPV16 E2)
Reactivity Human papilloma virus
Relevance The human papilloma virus (HPV) family of DNA tumor viruses includes HPV-16 and HPV-18, which are associated with a large proportion of cervical cancer cases. E1 and E2 are proteins involved in the regulation of viral DNA replication. TVG 261 is useful for detection of protein in cervical lesions.
Host Mouse
Immunogen Vaccinia-E2 followed by intravenous injection of the maltose binding protein MBP-E2 (generated from an expression vector in which the E2 ORF was cloned in frame with malE).
Subclass IgG1
Myeloma Used P3/NS1/1-Ag4.1
Recommended Growing Conditions DMEM + 5% FCS
Strain Balb/c
Research Area Cancer, Virology

References: 6 entries

Tchilian et al. 2001. J Immunol. 166(2):1308-13. PMID: 11145714.

A deletion in the gene encoding the CD45 antigen in a patient with SCID.

Europe PMC ID: 11145714

Zilch et al. 1998. Eur J Immunol. 28(1):22-9. PMID: 9485182.

A point mutation within CD45 exon A is the cause of variant CD45RA splicing in humans.

Europe PMC ID: 9485182

Hibma et al. 1995. Eur J Biochem. 229(2):517-25. PMID: 7744075.

The interaction between human papillomavirus type 16 E1 and E2 proteins is blocked by an antibody to the N-terminal region of E2.

Europe PMC ID: 7744075


Add a reference

References: 6 entries

Tchilian et al. 2001. J Immunol. 166(2):1308-13. PMID: 11145714.

A deletion in the gene encoding the CD45 antigen in a patient with SCID.

Europe PMC ID: 11145714

Zilch et al. 1998. Eur J Immunol. 28(1):22-9. PMID: 9485182.

A point mutation within CD45 exon A is the cause of variant CD45RA splicing in humans.

Europe PMC ID: 9485182

Hibma et al. 1995. Eur J Biochem. 229(2):517-25. PMID: 7744075.

The interaction between human papillomavirus type 16 E1 and E2 proteins is blocked by an antibody to the N-terminal region of E2.

Europe PMC ID: 7744075


Add a reference

References: 6 entries

Tchilian et al. 2001. J Immunol. 166(2):1308-13. PMID: 11145714.

A deletion in the gene encoding the CD45 antigen in a patient with SCID.

Zilch et al. 1998. Eur J Immunol. 28(1):22-9. PMID: 9485182.

A point mutation within CD45 exon A is the cause of variant CD45RA splicing in humans.

Hibma et al. 1995. Eur J Biochem. 229(2):517-25. PMID: 7744075.

The interaction between human papillomavirus type 16 E1 and E2 proteins is blocked by an antibody to the N-terminal region of E2.


Add a reference


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