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Anti-HPV16E2 [TVG 261]


Catalogue Number 151167
Applications ELISA WB
Antigen/Gene or Protein Targets Human Papilloma virus-16 early protein 2 (HPV16 E2)
Reactivity Human papilloma virus
Relevance The human papilloma virus (HPV) family of DNA tumor viruses includes HPV-16 and HPV-18, which are associated with a large proportion of cervical cancer cases. E1 and E2 are proteins involved in the regulation of viral DNA replication. TVG 261 is useful for detection of protein in cervical lesions.
Host Mouse
Immunogen Vaccinia-E2 followed by intravenous injection of the maltose binding protein MBP-E2 (generated from an expression vector in which the E2 ORF was cloned in frame with malE).
Subclass IgG1
Myeloma Used P3/NS1/1-Ag4.1
Recommended Growing Conditions DMEM + 5% FCS
Strain Balb/c
Research Area Cancer, Virology

References: 3 entries

Tchilian et al. 2001. J Immunol. 166(2):1308-13. PMID: 11145714.

Zilch et al. 1998. Eur J Immunol. 28(1):22-9. PMID: 9485182.

Hibma et al. 1995. Eur J Biochem. 229(2):517-25. PMID: 7744075.

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