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Anti-LewisX [TG-1]

Info

Catalogue Number 151165
Applications FACS IHC IF
Antigen/Gene or Protein Targets Lewis X (CD15)
Synonyms Fucosyltransferase 4; Galactoside 3-L-Fucosyltransferase; ELAM-1 Ligand Fucosyltransferase; FUC-TIV; FCT3A; ELFT; Stage-Specific Embryonic Antigen; Alpha (1,3) Fucosyltransferase; EC 2.4.1.65; Lewis X; SSEA-1; FUTIV; CD15; LeX
Reactivity Human
Relevance Lewis X (CD15) is a branched pentasaccharide found on neutrophils, eosinophils and monocytes. Lewis X is distributed abnormally in myeloid leukeamias and is commonly used in the diagnosis of Hodgkin’s disease. TG-1 is useful for the differentiation of human leukocytes.
Host Mouse
Immunogen Thymocyte glycoprotein fraction adsorbed to Con A and eluted with 0.1M glucose.
Subclass IgM
Molecular Weight (kDa) 156
Myeloma Used P3/NS1/1-Ag4.1
Recommended Growing Conditions DMEM + 5% FCS
Strain CBA
Notes TG-1 is cytotoxic with rabbit complement.
Research Area Cancer, Immunology

References: 4 entries

Cho et al. 2010. J Proteome Res. 9(11):5960-8. PMID: 20858014.

FACS

Hogg et al. 1984. Immunology. 53(4):753-67. PMID: 6389324.

Linch et al. 1984. Blood. 63(3):566-73. PMID: 6365201.

Beverley et al. 1980. Nature. 287(5780):332-3. PMID: 7421991.


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