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Anti-ErbB3 [SGP1]


Catalogue Number 151159
Applications FACS IHC IF IP
Antigen/Gene or Protein Targets ErbB3 (Her3)
Reactivity Human
Relevance The EGFR family of type I growth factor receptor tyrosine kinases includes EGFR (HER1), c-erbB2 (HER2; neu), c-erbB3 (HER3) and c-erbB4 (HER4). c-erbB3 is normally found in non-dividing differentiated epithelial cells, neurones and hepatocytes. It has approximately 80% prevalence in a wide variety of tumours of the gastro-intestinal tract, and approximately 20% prevalence in breast cancer.
Host Mouse
Immunogen c-erb B3 protein from transfected human kidney fibroblasts purified by wheatgerm lectin affinity chromatography
Subclass IgG1 kappa
Myeloma Used NS0
Recommended Growing Conditions DMEM + 5% FCS
Strain Balb/c
Research Area Cancer, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction

References: 3 entries

Vollmann-Zwerenz et al. 2010. Cytometry A. 77(4):387-98. PMID: 20151455.

Srinivasan et al. 1998. J Pathol. 185(3):236-45. PMID: 9771476.

Rajkumar et al. 1994. Br J Cancer. 70(3):459-65. PMID: 8080731.

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