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Anti-ErbB3 [RTJ1]


Catalogue Number 151157
Applications IHC IP WB
Antigen/Gene or Protein Targets ErbB3 (Her3)
Reactivity Human
Relevance The EGFR family of type I growth factor receptor tyrosine kinases includes EGFR (HER1), c-erbB2 (HER2; neu), c-erbB3 (HER3) and c-erbB4 (HER4). c-erbB3 is normally found in non-dividing differentiated epithelial cells, neurones and hepatocytes. It has approximately 80% prevalence in a wide variety of tumours of the gastro-intestinal tract, and approximately 20% prevalence in breast cancer.
Host Mouse
Immunogen Synthetic Peptide from C terminus of human c-erbB3
Subclass IgM
Myeloma Used NS0
Recommended Growing Conditions RPMI 1640 + 10% FCS
Research Area Cancer, Cell Type or Organelle Marker, Cell Signaling & Signal Transduction

References: 6 entries

Anagnostou et al. 2010. Cancer Epidemiol Biomarkers Prev. 19(4):982-91. PMID: 20332259.

Kapitanović et al. 2000. J Cancer Res Clin Oncol. 126(4):205-11. PMID: 10782893.

Naidu et al. 1998. Br J Cancer. 78(10):1385-90. PMID: 9823984.

Srinivasan et al. 1998. J Pathol. 185(3):236-45. PMID: 9771476.

Rajkumar et al. 1996. Clin Mol Pathol. 49(4):M199-202. PMID: 16696074.

Rajkumar et al. 1993. J Pathol. 170(3):271-8. PMID: 8133400.

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