Anti-Mast Cell [MCG35]
Invented at Queen Mary University of London
- Datasheet
- References (4)
- Inventor Info
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| Catalogue Number | 151132 |
| Applications | IHC |
| Antigen/Gene or Protein Targets | Mast cell marker |
| Reactivity | Human |
| Relevance | MCG25 is useful for mast cell identification in immunological reactions and hypersensitivity diseases e.g. allergy and asthma. The antigen is found in granule components of mast cells and may also be found intracytoplasmically in human mature small enterocytes, liver parenchymal cells and kidney proximal tubule epithelial cells. |
| Host | Mouse |
| Immunogen | Spleen cells and bone marrow cells (erythrocyte depleted) from a patient with systemic mastocytosis. The bone marrow preparation consisted of 50% typical mast cells. |
| Positive Control | The antigen is found in granule components of mast cells. |
| Subclass | IgG1 kappa |
| Myeloma Used | P3X63Ag8.653 |
| Recommended Growing Conditions | DMEM + 5% FCS |
| Strain | Balb/c |
| Notes | The antibody does not react with basophils or other haemopoietic cell types. |
| Research Area | Cardiovascular |
References: 4 entries
Rimmer et al. 1987. Clin Exp Immunol. 68(3):712-8. PMID: 3308221.
Origin of human mast cells studied by dual immunofluorescence.
Europe PMC ID: 3308221
Rimmer et al. 1984. J Clin Pathol. 37(11):1249-55. PMID: 6389604.
Human mast cells detected by monoclonal antibodies.
Europe PMC ID: 6389604
Add a reference
References: 4 entries
Rimmer et al. 1987. Clin Exp Immunol. 68(3):712-8. PMID: 3308221.
Origin of human mast cells studied by dual immunofluorescence.
Rimmer et al. 1984. J Clin Pathol. 37(11):1249-55. PMID: 6389604.
Human mast cells detected by monoclonal antibodies.
Add a reference
