Anti-CD1c [M241]
Invented by Prof Walter Bodmer from University of Oxford
Invented at Cancer Research UK London Research Institute: Lincoln's Inn Fields
- Datasheet
- References (10)
- Inventor Info
Info
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| Catalogue Number | 151130 |
| Applications | IHC IP RIA |
| Antigen/Gene or Protein Targets | CD1c (Human Thymus Leukaemia antigen) |
| Synonyms | CD1c Molecule; CD1C Antigen; C Polypeptide; CD1c Antigen; Differentiation Antigen CD1-Alpha-3; Cortical Thymocyte Antigen; CD1C; BDCA1; CD1A; CD1; R7 |
| Reactivity | Human |
| Relevance | Cluster of Differentiation 1c (CD1c) is one of five human CD1 isoforms, a family of b2-microglobulin-associated transmembrane proteins that bind and present lipid antigens to T cells. M241 is useful for identification and elimination of some leukaemias. |
| Host | Mouse |
| Immunogen | MOLT 4 cell line |
| Subclass | IgG1 |
| Molecular Weight (kDa) | 45 |
| Myeloma Used | P3/NS1/1-Ag4.1 |
| Recommended Growing Conditions | DMEM + 5% FCS |
| Strain | Balb/c |
| Research Area | Cancer, Cell Type or Organelle Marker, Immunology |
References: 10 entries
MiR-381-3p Regulates the Antigen-Presenting Capability of Dendritic Cells and Represses Antituberculosis Cellular Immune Responses by Targeting CD1c.
Europe PMC ID: 27296666
Wen et al. 2016. J Immunol. :. PMID: 27296666.
Small et al. 1989. Hum Immunol. 25(3):181-93. PMID: 2670851.
Characterization of B cells in severe combined immunodeficiency disease.
Europe PMC ID: 2670851
Merle-Beral et al. 1988. Eur J Haematol. 41(3):197-203. PMID: 3263283.
Phenotypic heterogeneity of B- and T-cell differentiation antigens in B-CLL.
Europe PMC ID: 3263283
Matsumoto et al. 1986. J Immunol. 137(9):2907-12. PMID: 2428878.
Functional analysis of activated C1s, a subcomponent of the first component of human complement, by monoclonal antibodies.
Europe PMC ID: 2428878
Knowles et al. 1982. Eur J Immunol. 12(8):676-81. PMID: 6754387.
A monoclonal antibody recognizing a human thymus leukemia-like antigen associated with beta 2-microglobulin.
Europe PMC ID: 6754387
Add a reference
References: 10 entries
MiR-381-3p Regulates the Antigen-Presenting Capability of Dendritic Cells and Represses Antituberculosis Cellular Immune Responses by Targeting CD1c.
Wen et al. 2016. J Immunol. :. PMID: 27296666.
Small et al. 1989. Hum Immunol. 25(3):181-93. PMID: 2670851.
Characterization of B cells in severe combined immunodeficiency disease.
Merle-Beral et al. 1988. Eur J Haematol. 41(3):197-203. PMID: 3263283.
Phenotypic heterogeneity of B- and T-cell differentiation antigens in B-CLL.
Matsumoto et al. 1986. J Immunol. 137(9):2907-12. PMID: 2428878.
Functional analysis of activated C1s, a subcomponent of the first component of human complement, by monoclonal antibodies.
Knowles et al. 1982. Eur J Immunol. 12(8):676-81. PMID: 6754387.
A monoclonal antibody recognizing a human thymus leukemia-like antigen associated with beta 2-microglobulin.
Add a reference
