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Anti-CD1c [M241]

Invented by Prof Walter Bodmer at University of Oxford

Info

Catalogue Number 151130
Applications IHC IP RIA
Antigen/Gene or Protein Targets CD1c (Human Thymus Leukaemia antigen)
Synonyms CD1c Molecule; CD1C Antigen; C Polypeptide; CD1c Antigen; Differentiation Antigen CD1-Alpha-3; Cortical Thymocyte Antigen; CD1C; BDCA1; CD1A; CD1; R7
Reactivity Human
Relevance Cluster of Differentiation 1c (CD1c) is one of five human CD1 isoforms, a family of b2-microglobulin-associated transmembrane proteins that bind and present lipid antigens to T cells. M241 is useful for identification and elimination of some leukaemias.
Host Mouse
Immunogen MOLT 4 cell line
Subclass IgG1
Molecular Weight (kDa) 45
Myeloma Used P3/NS1/1-Ag4.1
Recommended Growing Conditions DMEM + 5% FCS
Strain Balb/c
Research Area Cancer, Cell Type or Organelle Marker, Immunology

References: 10 entries

MiR-381-3p Regulates the Antigen-Presenting Capability of Dendritic Cells and Represses Antituberculosis Cellular Immune Responses by Targeting CD1c.

Europe PMC ID: 27296666

Wen et al. 2016. J Immunol. :. PMID: 27296666.

Small et al. 1989. Hum Immunol. 25(3):181-93. PMID: 2670851.

Characterization of B cells in severe combined immunodeficiency disease.

Europe PMC ID: 2670851

Merle-Beral et al. 1988. Eur J Haematol. 41(3):197-203. PMID: 3263283.

Phenotypic heterogeneity of B- and T-cell differentiation antigens in B-CLL.

Europe PMC ID: 3263283

Matsumoto et al. 1986. J Immunol. 137(9):2907-12. PMID: 2428878.

Functional analysis of activated C1s, a subcomponent of the first component of human complement, by monoclonal antibodies.

Europe PMC ID: 2428878

Knowles et al. 1982. Eur J Immunol. 12(8):676-81. PMID: 6754387.

A monoclonal antibody recognizing a human thymus leukemia-like antigen associated with beta 2-microglobulin.

Europe PMC ID: 6754387


Add a reference

References: 10 entries

MiR-381-3p Regulates the Antigen-Presenting Capability of Dendritic Cells and Represses Antituberculosis Cellular Immune Responses by Targeting CD1c.

Europe PMC ID: 27296666

Wen et al. 2016. J Immunol. :. PMID: 27296666.

Small et al. 1989. Hum Immunol. 25(3):181-93. PMID: 2670851.

Characterization of B cells in severe combined immunodeficiency disease.

Europe PMC ID: 2670851

Merle-Beral et al. 1988. Eur J Haematol. 41(3):197-203. PMID: 3263283.

Phenotypic heterogeneity of B- and T-cell differentiation antigens in B-CLL.

Europe PMC ID: 3263283

Matsumoto et al. 1986. J Immunol. 137(9):2907-12. PMID: 2428878.

Functional analysis of activated C1s, a subcomponent of the first component of human complement, by monoclonal antibodies.

Europe PMC ID: 2428878

Knowles et al. 1982. Eur J Immunol. 12(8):676-81. PMID: 6754387.

A monoclonal antibody recognizing a human thymus leukemia-like antigen associated with beta 2-microglobulin.

Europe PMC ID: 6754387


Add a reference

References: 10 entries

MiR-381-3p Regulates the Antigen-Presenting Capability of Dendritic Cells and Represses Antituberculosis Cellular Immune Responses by Targeting CD1c.

Wen et al. 2016. J Immunol. :. PMID: 27296666.

Small et al. 1989. Hum Immunol. 25(3):181-93. PMID: 2670851.

Characterization of B cells in severe combined immunodeficiency disease.

Merle-Beral et al. 1988. Eur J Haematol. 41(3):197-203. PMID: 3263283.

Phenotypic heterogeneity of B- and T-cell differentiation antigens in B-CLL.

Matsumoto et al. 1986. J Immunol. 137(9):2907-12. PMID: 2428878.

Functional analysis of activated C1s, a subcomponent of the first component of human complement, by monoclonal antibodies.

Knowles et al. 1982. Eur J Immunol. 12(8):676-81. PMID: 6754387.

A monoclonal antibody recognizing a human thymus leukemia-like antigen associated with beta 2-microglobulin.


Add a reference


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