Anti-Leu2 [M236]
Invented by Prof Walter Bodmer from University of Oxford
Invented at Cancer Research UK London Research Institute: Lincoln's Inn Fields
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- References (1)
- Inventor Info
Info
| Catalogue Number | 151129 |
| Applications | IHC IP RIA |
| Antigen/Gene or Protein Targets | Leu2 (CD8) |
| Reactivity | Human |
| Relevance | Leu-2 is a T cell co-receptor that recognises, together with the T cell receptor, MHC class I molecules. Leu-2 is present on human suppressor / cytotoxic T cells, 30% of circulating T cells. M236 is useful for the identification of cytotoxic/suppressor cell subpopulation in peripheral blood, elimination of cytotoxic/suppressor cell subpopulation from peripheral blood and bone marrow, elimination of some T cell leukaemias and blocking of cytotoxic activity. |
| Host | Mouse |
| Immunogen | MOLT 4 cell line. |
| Subclass | IgG1 |
| Molecular Weight (kDa) | 32 |
| Myeloma Used | P3/NS1/1-Ag4.1 |
| Recommended Growing Conditions | DMEM + 5% FCS |
| Strain | Balb/c |
| Research Area | Immunology, Stem Cell Biology |
References: 1 entry
1st International Workshop on Human Leucocyte Differentiation Antigans (code T67), Paris, November 1982
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References: 1 entry
1st International Workshop on Human Leucocyte Differentiation Antigans (code T67), Paris, November 1982
Add a reference