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Anti-Leu2 [M236]


Catalogue Number 151129
Applications IHC IP RIA
Antigen/Gene or Protein Targets Leu2 (CD8)
Reactivity Human
Relevance Leu-2 is a T cell co-receptor that recognises, together with the T cell receptor, MHC class I molecules. Leu-2 is present on human suppressor / cytotoxic T cells, 30% of circulating T cells. M236 is useful for the identification of cytotoxic/suppressor cell subpopulation in peripheral blood, elimination of cytotoxic/suppressor cell subpopulation from peripheral blood and bone marrow, elimination of some T cell leukaemias and blocking of cytotoxic activity.
Host Mouse
Immunogen MOLT 4 cell line.
Subclass IgG1
Molecular Weight (kDa) 32
Myeloma Used P3/NS1/1-Ag4.1
Recommended Growing Conditions DMEM + 5% FCS
Strain Balb/c
Research Area Immunology, Stem Cell Biology

References: 1 entry

1st International Workshop on Human Leucocyte Differentiation Antigans (code T67), Paris, November 1982

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