Anti-Keratin7 [LP5K]
Invented by Prof Birgit Lane from A*STAR Accelerate Technologies Pte Ltd
Invented at Queen Mary University of London
- Datasheet
- References (7)
- Inventor Info
Info
| Catalogue Number | 151127 |
| Applications | FACS IHC IF WB |
| Antigen/Gene or Protein Targets | Keratin 7 |
| Reactivity | Human |
| Relevance | Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratins 7 and 8 are two closely related type II keratins characteristic of simple epithelia. Keratin 7 is less widespread than keratin 8 and is expressed in sebaceous and sweat glands and some cells of the inner hair root sheath. Keratin 7 is often co-expressed with keratin 19. |
| Host | Mouse |
| Immunogen | Sonicated cytoskeleton fractions (insoluble in 1% Nonidet-P40) from SV40 transformed neonatal keratinocytes. |
| Subclass | IgG2b |
| Molecular Weight (kDa) | 54 |
| Myeloma Used | Sp2/0-Ag14 |
| Recommended Growing Conditions | DMEM + 5% FCS |
| Strain | Balb/c |
| Notes | Reacts with human keratin 7 & 8 |
| Research Area | Cell Signaling & Signal Transduction |
References: 7 entries
Lane EB et al. 1985. Ann. NY Acad. Sci. 455:241-58.PMID: 2417515
Sato et al. 2005. Blood. 106(2):428-35. PMID: 15797992.
Platelet-derived soluble factors induce human extravillous trophoblast migration and differentiation: platelets are a possible regulator of trophoblast infiltration into maternal spiral arteries.
Europe PMC ID: 15797992
Sato et al. 2003. Development. 130(22):5519-32. PMID: 14530297.
Trophoblasts acquire a chemokine receptor, CCR1, as they differentiate towards invasive phenotype.
Europe PMC ID: 14530297
Markey et al. 1991. J Invest Dermatol. 97(5):763-70. PMID: 1717607.
Expression of simple epithelial keratins 8 and 18 in epidermal neoplasia.
Europe PMC ID: 1717607
Add a reference
References: 7 entries
Lane EB et al. 1985. Ann. NY Acad. Sci. 455:241-58.PMID: 2417515
Sato et al. 2005. Blood. 106(2):428-35. PMID: 15797992.
Platelet-derived soluble factors induce human extravillous trophoblast migration and differentiation: platelets are a possible regulator of trophoblast infiltration into maternal spiral arteries.
Sato et al. 2003. Development. 130(22):5519-32. PMID: 14530297.
Trophoblasts acquire a chemokine receptor, CCR1, as they differentiate towards invasive phenotype.
Markey et al. 1991. J Invest Dermatol. 97(5):763-70. PMID: 1717607.
Expression of simple epithelial keratins 8 and 18 in epidermal neoplasia.
Add a reference
