Anti-Keratin6 [LL020]
Invented by Prof Irene Leigh from Queen Mary University of London
Invented at Cancer Research UK London Research Institute: Clare Hall Laboratories
- Datasheet
- References (4)
- Inventor Info
Info
| Catalogue Number | 151122 |
| Applications | IHC IF WB |
| Antigen/Gene or Protein Targets | Keratin 6 |
| Reactivity | Human |
| Relevance | Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratins 6 is expressed in suprabasal keratinocytes of wounded epidermis and in acrosyringeal keratinocytes in normal skin. LL020 can be used as a proliferation marker. |
| Host | Mouse |
| Immunogen | Carboxy terminal peptide |
| Subclass | IgM |
| Myeloma Used | Sp2/0-Ag14 |
| Recommended Growing Conditions | DMEM + 5% FCS |
| Notes | Immunoperoxidase is recommended for use on frozen sections for this antibody. |
| Research Area | Cell Signaling & Signal Transduction |
References: 4 entries
Hughes et al. 1996. Br J Dermatol. 134(2):247-56. PMID: 8746337.
Keratin expression in pilosebaceous epithelia in truncal skin of acne patients.
Europe PMC ID: 8746337
Markey et al. 1992. Br J Dermatol. 126(2):154-60. PMID: 1371396.
Keratin expression in basal cell carcinomas.
Europe PMC ID: 1371396
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References: 4 entries
Hughes et al. 1996. Br J Dermatol. 134(2):247-56. PMID: 8746337.
Keratin expression in pilosebaceous epithelia in truncal skin of acne patients.
Markey et al. 1992. Br J Dermatol. 126(2):154-60. PMID: 1371396.
Keratin expression in basal cell carcinomas.
Add a reference
