Anti-ICAM3 [ICAM 3.1]
Invented at University of Oxford
- Datasheet
- References (3)
- Inventor Info
Info
| Catalogue Number | 151110 |
| Applications | ELISA FACS IHC IF IP RIA WB |
| Antigen/Gene or Protein Targets | ICAM3 (CD50) |
| Synonyms | Intercellular Adhesion Molecule 3; ICAM-3; ICAM-R; CDW50; CD50 |
| Reactivity | Human |
| Relevance | ICAMs are members of the immunoglobulin superfamily that is characterised by the presence of immunoglobulin-like domains. ICAM-3 is the major ligand for LFA-1 (CD11a/CD18) in the resting state. ICAM-3 may play a key role in initiating immune responses. ICAM 3.1 and ICAM 3.2 can be used to examine LFA-1/ICAM-3 adhesion. |
| Host | Mouse |
| Immunogen | ICAM-3Fc chimeric fusion protein. |
| Subclass | IgG1 |
| Molecular Weight (kDa) | 130 |
| Myeloma Used | Sp2/0-Ag14 |
| Recommended Growing Conditions | DMEM + 5% FCS |
| Research Area | Adhesion, Cell Signaling & Signal Transduction, Immunology |
References: 3 entries
DC-SIGN binds ICAM-3 isolated from peripheral human leukocytes through Lewis x residues.
Europe PMC ID: 17145745
Increase in lymphoid follicles and leukocyte adhesion molecules emphasizes a role for the gut in spondyloarthropathy pathogenesis.
Europe PMC ID: 12434422
Analysis of the binding site on intercellular adhesion molecule 3 for the leukocyte integrin lymphocyte function-associated antigen 1.
Europe PMC ID: 7822326
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References: 3 entries
DC-SIGN binds ICAM-3 isolated from peripheral human leukocytes through Lewis x residues.
Increase in lymphoid follicles and leukocyte adhesion molecules emphasizes a role for the gut in spondyloarthropathy pathogenesis.
Analysis of the binding site on intercellular adhesion molecule 3 for the leukocyte integrin lymphocyte function-associated antigen 1.
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