Anti-PLAP [HD 11F7]
Invented by Prof Walter Bodmer at University of Oxford
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Info
| Catalogue Number | 151106 |
| Applications | ELISA IHC RIA |
| Antigen/Gene or Protein Targets | Placental alkaline phosphatase (PLAP) |
| Reactivity | Human |
| Relevance | Alkaline phosphatases are phosphodiesterases. The placental-specific isozyme of Alkaline Phosphatase (PLAP) is found in trophoblast cells of normal human mature placenta, seminomas of testis and ovarian carcinomas. The detection of alkaline phosphatase in serum is a marker for ovarian and testicular cancer. HD 11F7 has potential uses in the diagnosis of ovarian and testicular tumours. The antibody detects both Regan and Nagao isoenzymes. |
| Host | Mouse |
| Immunogen | Fresh Hep-2 cells followed by booster injections of fresh Hep-2 cells that had their surface expression of PLAP boosted in culture. |
| Subclass | IgG2b |
| Myeloma Used | P3/NS1/1-Ag4.1 |
| Recommended Growing Conditions | DMEM + 5% FCS |
| Strain | Balb/c |
| Research Area | Cancer, Cell Type or Organelle Marker |
References: 1 entry
References: 1 entry
References: 1 entry
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