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Anti-HPV18E6 [BF7]


Catalogue Number 151080
Applications ELISA RIA WB
Antigen/Gene or Protein Targets Human Papilloma Virus-18 early protein 6 (HPV18 E6)
Reactivity Virus
Relevance The human papilloma virus (HPV) family of DNA tumor viruses includes HPV-16 and HPV-18, which are associated with a large proportion of cervical cancer cases. HPV early proteins E6 and E7 are the major viral oncoproteins that regulate cell proliferation through the inactivation of p53 and Rb1 tumour suppressor proteins respectively. BF7 can be used for detection of HPV in cervical smears and biopsies and analysis of E6 expression in cell transformation studies.
Host Mouse
Immunogen Gel-purified HPV-18 E6-b galactosidase fusion protein.
Subclass IgG1
Positive Control HPV infected tissue
Molecular Weight (kDa) 16.5
Myeloma Used P3/NS1/1-Ag4.1
Recommended Growing Conditions DMEM + 5% FCS
Strain Balb/c
Notes Reactivity: Herpes simplex virus (HSV)
Research Area Cancer, Virology

References: 1 entry

Banks et al. 1987. J Gen Virol. 68 ( Pt 5):1351-9. PMID: 3033140.

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