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Anti-Keratin19 [BA17]

Info

Catalogue Number 151077
Applications FACS IHC IP WB
Antigen/Gene or Protein Targets Keratin 19
Reactivity Human
Relevance Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Keratin 19 (a cytokeratin) is the smallest human keratin and is found in many simple and some non-keratinising stratified squamous epithelia. The degree of keratin 19 positivity in breast cancer distinguishes malignant from benign tumours. Keratin 19 is often co-expressed with keratin 7.
Host Mouse
Immunogen Detergent-insoluble extract of human mammary epithelial organoids.
Subclass IgG1
Myeloma Used P3X63Ag8.653
Recommended Growing Conditions DMEM + 5% FCS
Strain Balb/c
Research Area Cell Signaling & Signal Transduction

References: 6 entries

Morton et al. 2008. Am J Pathol. 172(4):1081-7. PMID: 18310506.

Aleksic et al. 2007. Gut. 56(2):227-36. PMID: 16870717.

Nightingale et al. 2004. J Am Soc Nephrol. 15(1):21-32. PMID: 14694154.

Bártek et al. 1986. Eur J Cancer Clin Oncol. 22(12):1441-52. PMID: 2439341.

Bartek et al. 1985. Int J Cancer. 36(3):299-306. PMID: 2411673.

Bartek et al. 1985. J Cell Sci. 75:17-33. PMID: 2413060.


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