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Monoclonal Antibodies

Anti-EpCAM [AUA1]

Invented by Prof Walter Bodmer from University of Oxford
Invented at Cancer Research UK London Research Institute: Lincoln's Inn Fields
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  • Inventor Info
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Info

Catalogue Number 151075
Applications ELISA FACS IHC IF IP WB
Antigen/Gene or Protein Targets Epithelial Cell Adhesion Molecule (EpCAM, CD326)
Reactivity Human
Relevance AUA1 cross reacts with breast carcinomas, kidney tubules, tonsil crypt epithelium and cells in some serious effusions. This is a good antibody for characterisation of all epithelial cells.
Host Mouse
Immunogen LoVo cell line, a colon carcinoma cell line.
Subclass IgG1
Molecular Weight (kDa) 40
Myeloma Used P3X63Ag8
Recommended Growing Conditions DMEM + 5% FCS
Strain Balb/c
Research Area Cancer, Cell Type or Organelle Marker

References

There are 19 reference entries for this reagent.

View All References

References: 19 entries

Hsia et al. 2016. Proc Natl Acad Sci U S A. :. PMID: 27036009.

IP WB

View  

Myofibroblasts are distinguished from activated skin fibroblasts by the expression of AOC3 and other associated markers.

Europe PMC ID: 27036009

View  

Screening of carcinoma metastasis by flow cytometry: A study of 238 cases.

Europe PMC ID: 26054018

View  

Acosta et al. 2015. Cytometry B Clin Cytom. :. PMID: 26054018.

FACS

View  

Yeung et al. 2013. Br J Cancer. 108(10):2106-15. PMID: 23652304.

IHC IF

View  

Myofibroblast activation in colorectal cancer lymph node metastases.

Europe PMC ID: 23652304

View  

Yeung et al. 2010. Proc Natl Acad Sci U S A. 107(8):3722-7. PMID: 20133591.

IF

View  

Cancer stem cells from colorectal cancer-derived cell lines.

Europe PMC ID: 20133591

View  

Gaster et al. 2009. Nat Med. 15(11):1327-32. PMID: 19820717.

View  

Matrix-insensitive protein assays push the limits of biosensors in medicine.

Europe PMC ID: 19820717

View  

Ntouroupi et al. 2008. Br J Cancer. 99(5):789-95. PMID: 18682708.

IHC

View  

Detection of circulating tumour cells in peripheral blood with an automated scanning fluorescence microscope.

Europe PMC ID: 18682708

View  

Shaw et al. 2008. Cancer Cell Int. 8:3. PMID: 18348720.

View  

Inhibition of androgen-independent prostate cancer cell growth is enhanced by combination therapy targeting Hedgehog and ErbB signalling.

Europe PMC ID: 18348720

View  

Moss et al. 1988. Lung Cancer. 4, 76-78.

Epenetos et al. 1982. Lancet. 2(8306):1004-6. PMID: 6127499.

View  

Use of two epithelium-specific monoclonal antibodies for diagnosis of malignancy in serous effusions.

Europe PMC ID: 6127499

View  

Epenetos et al. 1982. Br J Cancer. 46(1):1-8. PMID: 7104190.

View  

Detection of human cancer in an animal model using radio-labelled tumour-associated monoclonal antibodies.

Europe PMC ID: 7104190

View  

Add a reference

References: 19 entries

Hsia et al. 2016. Proc Natl Acad Sci U S A. :. PMID: 27036009.

IP WB

View  

Myofibroblasts are distinguished from activated skin fibroblasts by the expression of AOC3 and other associated markers.

View  

Screening of carcinoma metastasis by flow cytometry: A study of 238 cases.

View  

Acosta et al. 2015. Cytometry B Clin Cytom. :. PMID: 26054018.

FACS

View  

Yeung et al. 2013. Br J Cancer. 108(10):2106-15. PMID: 23652304.

IHC IF

View  

Myofibroblast activation in colorectal cancer lymph node metastases.

View  

Yeung et al. 2010. Proc Natl Acad Sci U S A. 107(8):3722-7. PMID: 20133591.

IF

View  

Cancer stem cells from colorectal cancer-derived cell lines.

View  

Gaster et al. 2009. Nat Med. 15(11):1327-32. PMID: 19820717.

View  

Matrix-insensitive protein assays push the limits of biosensors in medicine.

View  

Ntouroupi et al. 2008. Br J Cancer. 99(5):789-95. PMID: 18682708.

IHC

View  

Detection of circulating tumour cells in peripheral blood with an automated scanning fluorescence microscope.

View  

Shaw et al. 2008. Cancer Cell Int. 8:3. PMID: 18348720.

View  

Inhibition of androgen-independent prostate cancer cell growth is enhanced by combination therapy targeting Hedgehog and ErbB signalling.

View  

Moss et al. 1988. Lung Cancer. 4, 76-78.

Epenetos et al. 1982. Lancet. 2(8306):1004-6. PMID: 6127499.

View  

Use of two epithelium-specific monoclonal antibodies for diagnosis of malignancy in serous effusions.

View  

Epenetos et al. 1982. Br J Cancer. 46(1):1-8. PMID: 7104190.

View  

Detection of human cancer in an animal model using radio-labelled tumour-associated monoclonal antibodies.

View  

Add a reference

Inventor Information