Anti-ADA [ADA-1]
Invented by Julian Gannon from The Francis Crick Institute
Invented at Cancer Research UK London Research Institute: Clare Hall Laboratories
- Datasheet
- References (3)
- Inventor Info
Info
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| Catalogue Number | 151072 |
| Applications | IHC IP RIA WB |
| Antigen/Gene or Protein Targets | ADA protein |
| Reactivity | E.coli |
| Relevance | Ada is an O6-methylguanine DNA methyltransferase that protects against DNA alkylation by the repair of methylated bases. Ada also functions as a positive regulator of the adaptive response to DNA alkylation damage. Induction of the Ada protein is a sign of environmentally caused mutagenesis in bacteria. |
| Host | Mouse |
| Immunogen | ADA protein |
| Subclass | IgG1 kappa |
| Myeloma Used | Sp2/0-Ag14 |
| Recommended Growing Conditions | DMEM + 5% FCS |
| Strain | Balb/c |
| Research Area | Bacteriology, Cancer, DNA Damage and Repair, Epigenetics & Nuclear Signalling, Metabolism |
References: 3 entries
McCormack et al. 2015. Elife. 4:. PMID: 26402460.
WB
Vaughan et al. 1991. Carcinogenesis. 12(2):263-8. PMID: 1995192.
Environmental mutagens that induce the adaptive response to alkylating agents in Escherichia coli.
Europe PMC ID: 1995192
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References: 3 entries
McCormack et al. 2015. Elife. 4:. PMID: 26402460.
WB
Vaughan et al. 1991. Carcinogenesis. 12(2):263-8. PMID: 1995192.
Environmental mutagens that induce the adaptive response to alkylating agents in Escherichia coli.
Add a reference
