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Anti-XPG [8H7/XPG]

Info

Catalogue Number 151063
Applications ELISA FACS IHC IF IP WB
Antigen/Gene or Protein Targets XPG
Reactivity Human
Relevance XPG is a DNA endonuclease that is essential for the dual incision step of nucleotide excision repair (cleaves 3' of the DNA lesion). XPG might be involved in the DNA replication and repair deficiency syndromes Cockayne Syndrome and Xeroderma pigmentosa.
Host Mouse
Immunogen Recombinant human XPG protein produced in baculovirus
Subclass IgG2a
Positive Control LnCap cells
Molecular Weight (kDa) 185
Myeloma Used Sp2/0-Ag14
Recommended Growing Conditions DMEM + 5% FCS
Strain Balb/c
Notes 8H7/XPG stains XPG in the nuclei of human cells.
Research Area DNA Damage and Repair, Epigenetics & Nuclear Signalling

References: 10 entries

HCMV-infected cells maintain efficient nucleotide excision repair of the viral genome while abrogating repair of the host genome.

Europe PMC ID: 23209410

O'Dowd et al. 2012. PLoS Pathog. 8(11):e1003038. PMID: 23209410.

IF

Igoucheva et al. 2006. Oligonucleotides. 16(1):94-104. PMID: 16584298.

Bomgarden et al. 2006. EMBO J. 25(11):2605-14. PMID: 16675950.

Opposing effects of the UV lesion repair protein XPA and UV bypass polymerase eta on ATR checkpoint signaling.

Europe PMC ID: 16675950

Involvement of ERCC1/XPF and XPG in oligodeoxynucleotide-directed gene modification.

Europe PMC ID: 16584298

Araújo et al. 2001. Mol Cell Biol. 21(7):2281-91. PMID: 11259578.

Strong functional interactions of TFIIH with XPC and XPG in human DNA nucleotide excision repair, without a preassembled repairosome.

Europe PMC ID: 11259578

Evans et al. 1997. EMBO J. 16(3):625-38. PMID: 9034344.

Open complex formation around a lesion during nucleotide excision repair provides a structure for cleavage by human XPG protein.

Europe PMC ID: 9034344


Add a reference

References: 10 entries

HCMV-infected cells maintain efficient nucleotide excision repair of the viral genome while abrogating repair of the host genome.

Europe PMC ID: 23209410

O'Dowd et al. 2012. PLoS Pathog. 8(11):e1003038. PMID: 23209410.

IF

Igoucheva et al. 2006. Oligonucleotides. 16(1):94-104. PMID: 16584298.

Bomgarden et al. 2006. EMBO J. 25(11):2605-14. PMID: 16675950.

Opposing effects of the UV lesion repair protein XPA and UV bypass polymerase eta on ATR checkpoint signaling.

Europe PMC ID: 16675950

Involvement of ERCC1/XPF and XPG in oligodeoxynucleotide-directed gene modification.

Europe PMC ID: 16584298

Araújo et al. 2001. Mol Cell Biol. 21(7):2281-91. PMID: 11259578.

Strong functional interactions of TFIIH with XPC and XPG in human DNA nucleotide excision repair, without a preassembled repairosome.

Europe PMC ID: 11259578

Evans et al. 1997. EMBO J. 16(3):625-38. PMID: 9034344.

Open complex formation around a lesion during nucleotide excision repair provides a structure for cleavage by human XPG protein.

Europe PMC ID: 9034344


Add a reference

References: 10 entries

HCMV-infected cells maintain efficient nucleotide excision repair of the viral genome while abrogating repair of the host genome.

O'Dowd et al. 2012. PLoS Pathog. 8(11):e1003038. PMID: 23209410.

IF

Igoucheva et al. 2006. Oligonucleotides. 16(1):94-104. PMID: 16584298.

Bomgarden et al. 2006. EMBO J. 25(11):2605-14. PMID: 16675950.

Opposing effects of the UV lesion repair protein XPA and UV bypass polymerase eta on ATR checkpoint signaling.

Involvement of ERCC1/XPF and XPG in oligodeoxynucleotide-directed gene modification.

Araújo et al. 2001. Mol Cell Biol. 21(7):2281-91. PMID: 11259578.

Strong functional interactions of TFIIH with XPC and XPG in human DNA nucleotide excision repair, without a preassembled repairosome.

Evans et al. 1997. EMBO J. 16(3):625-38. PMID: 9034344.

Open complex formation around a lesion during nucleotide excision repair provides a structure for cleavage by human XPG protein.


Add a reference


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