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Anti-XPA [5A2]


Catalogue Number 151058
Applications ELISA WB
Antigen/Gene or Protein Targets XPA
Reactivity Human
Relevance XPA binds to the Replication Protein A (RPA) and is a core component of the nucleotide excision repair pathway. XPA is involved in one of the complementation groups of the heritable condition Xeroderma pigmentosum, where defects in nucleotide excision repair result in increased susceptibility to mutagens including UV.
Host Mouse
Immunogen HIS-tagged recombinant human XPA protein.
Subclass IgG1
Positive Control LS174T, MCF-7 cells or human tonsil
Molecular Weight (kDa) 40
Myeloma Used Sp2/0-Ag14
Recommended Growing Conditions DMEM + 5% FCS
Strain Balb/c
Research Area DNA Damage and Repair, Epigenetics & Nuclear Signalling

References: 3 entries

Wei et al. 2005. Cancer Epidemiol Biomarkers Prev. 14(8):1961-6. PMID: 16103444.

Welsh et al. 2004. Int J Cancer. 110(3):352-61. PMID: 15095299.

Köberle et al. 1999. Curr Biol. 9(5):273-6. PMID: 10074455.

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