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Anti-LewisX [28]


Catalogue Number 151041
Applications FACS IHC IP
Antigen/Gene or Protein Targets Lewis X (CD15)
Synonyms Fucosyltransferase 4; Galactoside 3-L-Fucosyltransferase; ELAM-1 Ligand Fucosyltransferase; FUC-TIV; FCT3A; ELFT; Stage-Specific Embryonic Antigen; Alpha (1,3) Fucosyltransferase; EC; Lewis X; SSEA-1; FUTIV; CD15; LeX
Reactivity Human
Relevance Lewis X (CD15) is a branched pentasaccharide found on neutrophils, eosinophils and monocytes. Lewis X is distributed abnormally in myeloid leukeamias and is commonly used in the diagnosis of Hodgkin’s disease. It can also be used for analysis of myeloid leukaemias and studies of myeloid differentiation.
Host Mouse
Immunogen Monocytes, separated from other peripheral blood leucocytes (PBL) on fibronectin plates.
Subclass IgM
Molecular Weight (kDa) 83
Myeloma Used Sp2/0-Ag14
Recommended Growing Conditions DMEM + 5% FCS
Strain Balb/c
Notes Clone 28 does not activate complement.
Research Area Cancer, Immunology

References: 2 entries

Hogg et al. 1984. Immunology. 53(4):753-67. PMID: 6389324.

Linch et al. 1984. Blood. 63(3):566-73. PMID: 6365201.

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