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|Applications||ELISA FACS IHC IP|
|Antigen/Gene or Protein Targets||CD8|
|Relevance||CD8 is a T cell co-receptor that recognises, together with the T cell receptor, MHC class I molecules. CD8 is present on human suppressor / cytotoxic T cells, 30% of circulating T cells. Clone 14 is recommended for: the detection of immunoregulatory T cell subset imbalances in autoimmune disorders and immunodeficiency states, categorisation of T cell acute lymphoblastic leukaemia and lymphoblastic lymphoma in conjunction with other antigens and determination of CD4/CD8 ratios in immune deficiencies, rheumatoid arthritis and multiple sclerosis.|
|Immunogen||Fibronectin-purified human monocytes|
|Recommended Growing Conditions||DMEM + 5% FCS|
Recommended for T-cell enrichment by cell sorting or panning.
Suitability for western blotting not known; to be confirmed - therefore WB not listed as a definite application.
|Research Area||Cancer, Immunology, Stem Cell Biology|
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