Cancer Research Technology
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Catalogue Number 151035
Applications ELISA FACS IHC IP
Antigen/Gene or Protein Targets CD8
Synonyms Leu2
Reactivity Human
Relevance CD8 is a T cell co-receptor that recognises, together with the T cell receptor, MHC class I molecules. CD8 is present on human suppressor / cytotoxic T cells, 30% of circulating T cells. Clone 14 is recommended for: the detection of immunoregulatory T cell subset imbalances in autoimmune disorders and immunodeficiency states, categorisation of T cell acute lymphoblastic leukaemia and lymphoblastic lymphoma in conjunction with other antigens and determination of CD4/CD8 ratios in immune deficiencies, rheumatoid arthritis and multiple sclerosis.
Host Mouse
Immunogen Fibronectin-purified human monocytes
Subclass IgG1
Recommended Growing Conditions DMEM + 5% FCS
Notes Recommended for T-cell enrichment by cell sorting or panning.

Suitability for western blotting not known; to be confirmed - therefore WB not listed as a definite application.
Research Area Cancer, Immunology, Stem Cell Biology

References: 2 entries

Hogg et al. 1999. J Clin Invest. 103(1):97-106. PMID: 9884339.

A novel leukocyte adhesion deficiency caused by expressed but nonfunctional beta2 integrins Mac-1 and LFA-1.

Europe PMC ID: 9884339


Add a reference

References: 2 entries

Hogg et al. 1999. J Clin Invest. 103(1):97-106. PMID: 9884339.

A novel leukocyte adhesion deficiency caused by expressed but nonfunctional beta2 integrins Mac-1 and LFA-1.

Europe PMC ID: 9884339


Add a reference

References: 2 entries

Hogg et al. 1999. J Clin Invest. 103(1):97-106. PMID: 9884339.

A novel leukocyte adhesion deficiency caused by expressed but nonfunctional beta2 integrins Mac-1 and LFA-1.


Add a reference


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