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Anti-FCGR1 [10.1]

Info

Catalogue Number 151026
Applications FACS IHC IF IP Fn
Antigen/Gene or Protein Targets Fc-gamma receptor 1 (FCGR1, CD64)
Synonyms Fc Fragment Of IgG Receptor Ia; Fc Gamma Receptor Ia; Fc-Gamma RIA; IGFR1; FCRI; Fc Gamma Receptor; CD64 Antigen; FCGR1; CD64; FCG1
Reactivity Human
Relevance Fc-gamma receptor 1 (CD64) is an IgG receptor expressed by monocytes and myeloid cell lines. It is a marker of iflammation. It is involved in cancer and many chronic diseases (arthritis, multiple sclerosis, diabetic ulcers), but also in antibody-dependent cell-mediated cytotoxicity (ADCC), sepsis, automimmune disorders and periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome. The 10.1 antibody blocks the Ig binding to FcR1 receptor.
Host Mouse
Immunogen Rheumatoid synovial fluid cells and fibronectin purified human monocytes.
Subclass IgG1
Positive Control Myeloid cell lines U937 and HL60
Molecular Weight (kDa) 71
Myeloma Used Sp2/0-Ag14
Recommended Growing Conditions DMEM + 5% FCS
Strain Balb/c
Research Area Cancer, Immunology

References: 14 entries

Sips et al. 2016. Mucosal Immunol. :. PMID: 26883728.

Tan et al. 2016. Eur J Immunol. :. PMID: 26763072.

FACS

Hanihara et al. 2015. J Neurosurg. :1-8. PMID: 26636389.

Rogers et al. 2015. Cytometry B Clin Cytom. :. PMID: 26566003.

Tutt et al. 2015. J Immunol. :. PMID: 26512139.

FACS

Schwab et al. 2015. Cell Rep. :. PMID: 26456831.

Sousa et al. 2015. Breast Cancer Res. 17(1):101. PMID: 26243145.

FACS

Conrad et al. 2015. Arthritis Res Ther. 17:179. PMID: 26178906.

FACS

Matt et al. 2015. Scand J Rheumatol. :1-10. PMID: 26084203.

Pilling et al. 2015. PLoS One. 10(3):e0119709. PMID: 25774777.

Sutherland et al. 2015. Curr Protoc Cytom. 72:6.37.1-6.37.29. PMID: 25827482.

Schleinitz et al. 2008. Arthritis Rheum. 58(10):3216-23. PMID: 18821690.

Jayaram et al. 1989. Clin Exp Immunol. 75(3):414-20. PMID: 2495203.

Dougherty et al. 1987. Eur J Immunol. 17(10):1453-9. PMID: 3500057.


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