Anti-Vascular endothelium [10]
Invented by Prof Nancy Hogg from Cancer Research UK London Research Institute: Lincoln's Inn Fields
Invented at Cancer Research UK London Research Institute: Lincoln's Inn Fields
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 151025 |
| Applications | IHC |
| Antigen/Gene or Protein Targets | Vascular endothelium marker |
| Reactivity | Human |
| Relevance |
Monoclonal antibody which specifically binds vascular endothelium tissue. Background and Research Application The vascular endothelium comprises the thin inner layer of cells lining arteries and veins, with an essential role in the regulation of blood vessel tone and cellular activity. This antibody may be used to study the synovial membrane in rheumatoid, osteoarthritic and traumatised joints as well as normal vasculature. Anti-vascular endothelium (10) reactivity is stronger on capillary endothelium and weaker on larger arteries and veins. |
| Host | Mouse |
| Immunogen | Fibronectin-purified human monocytes. |
| Subclass | IgM |
| Myeloma Used | Sp2/0-Ag14 |
| Recommended Growing Conditions | DMEM + 5% FCS |
| Strain | Balb/c |
| Notes |
Production Details Purified using multi-step affinity chromatography with protein A. Storage Conditions Store at -20 degrees frozen. Avoid repeated freeze/thaw cycles. Points of Interest This antibody reacts specifically with vascular endothelium and no other tissue. Concentration 1mg/ml as standard |
| Research Area | Cancer, Cardiovascular, Cell Type or Organelle Marker |
References: 2 entries
Palmer et al. 1985. Clin Exp Immunol. 59(3):529-38. PMID: 3886218.
Features of synovial membrane identified with monoclonal antibodies.
Europe PMC ID: 3886218
Add a reference
References: 2 entries
Palmer et al. 1985. Clin Exp Immunol. 59(3):529-38. PMID: 3886218.
Features of synovial membrane identified with monoclonal antibodies.
Add a reference
