Anti-CyclinB1 [V143.1]
Invented by Julian Gannon from The Francis Crick Institute
Invented at Cancer Research UK London Research Institute: Clare Hall Laboratories
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 151020 |
| Applications | WB |
| Antigen/Gene or Protein Targets | Cyclin B1 |
| Synonyms | CCNB1; Cyclin B1; G2/Mitotic-Specific Cyclin B1; CCNB |
| Reactivity | Mouse |
| Relevance | Cyclins bind to and regulate the activity of the Cyclin Dependent Protein Kinases (CDKs). Cyclin B1 is a marker of cell proliferation and a key component of the cell cycle progression machinery. Cyclin B1 may prove to be a prognostic marker in neoplasia. V143.1 is exceptionally good at detecting Cyclin B1 in western blots, giving a very strong signal with minimal background. |
| Host | Mouse |
| Immunogen | His tagged cyclin B1 (hamster) expressed in bacteria. |
| Subclass | IgG1 |
| Myeloma Used | Sp2/0-Ag14 |
| Recommended Growing Conditions | DMEM + 5% FCS |
| Notes | Recommended Concentration: 1ug/ml. |
| Research Area | Cancer, Cell Cycle, Epigenetics & Nuclear Signalling |
References: 2 entries
Shen et al. 2010. Cell Cycle. 9(23):4720-34. PMID: 21099356.
Female infertility in PDE3A(-/-) mice: polo-like kinase 1 (Plk1) may be a target of protein kinase A (PKA) and involved in meiotic arrest of oocytes from PDE3A(-/-) mice.
Europe PMC ID: 21099356
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References: 2 entries
Shen et al. 2010. Cell Cycle. 9(23):4720-34. PMID: 21099356.
Female infertility in PDE3A(-/-) mice: polo-like kinase 1 (Plk1) may be a target of protein kinase A (PKA) and involved in meiotic arrest of oocytes from PDE3A(-/-) mice.
Add a reference
