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|Applications||IHC IF IP WB|
|Antigen/Gene or Protein Targets||Cyclin A|
|Synonyms||CCNA1; Cyclin A1; Testicular Tissue Protein Li 34; CT146|
|Relevance||Cyclins bind to and regulate the activity of the Cyclin Dependent Protein Kinases (CDKs). Cyclin A is involved in the regulation of the cell cycle and is essential for progression through S phase. Cyclin A protein is absent in cells prior to S-phase, during which its levels increase and peak. Cyclin A is a marker for actively proliferating cells and for cells in S phase.|
|Immunogen||Bovine Cyclin A|
|Recommended Growing Conditions||DMEM + 5% FCS|
E72.1 has been used to co-immunoprecipitates CIP-1 in active trimeric complexes of cyclinA cdk-CIP-1.
E72.1 is not recommended for use on parrafin embedded specimens.
|Research Area||Cancer, Cell Cycle, Epigenetics & Nuclear Signalling|
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