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Ximbio offer recombinant antibodies. What are their advantages over standard monoclonals?

Manufactured in an animal-free system means that recombinant antibodies (rAbs) have a very high purity (>98%) level and minimal variation between batches, with the high yielding production processes allowing for large quantities of the recombinant antibodies to be produced in a very short period of time.

Unlike hybridoma-derived antibodies, recombinant antibodies can be reformatted to a different species, isotype or subtype. This opens up the possibility of switching antibodies into a more preferable format for in vitro or in vivo use.

Recombinant antibodies can be engineered at the genetic level enabling production of recombinant antibody fragments, e.g. Fab and F(ab’)2, bispecific antibodies, site-specific conjugation of antibodies and a myriad of other possibilities that are not available with conventional antibody technologies.

The manufacturing process  is entirely animal free, alleviating any animal welfare concerns associated with traditional monoclonal antibody manufacturing


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