Catalogue Number
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154833 |
Applications
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N/A
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Antigen/Gene or Protein Targets
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Rad51B
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Reactivity
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Human
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Relevance
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RAD51B is a Rad51 paralog. RAD51 is a eukaryotic homologue of E. coli RecA, a recombinase, and a component of the homologous recombination DNA repair pathway. RAD51 forms a nucleoprotein filament (through binding RAD52 and single stranded DNA that are exposed following double strand breaks) that initiates recombination. RAD51B is also a component for the homologous recombination pathway.
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Host
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Mouse
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Immunogen
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Rad51b 1h3/13 was raised against His-tagged human Rad51B, overexpressed in e.coli and purified on a talon affinity column under denaturing conditions, followed by gel purification on a SDS-PAGE.
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Subclass
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IgG2a
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Research Area
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DNA Damage and Repair, Epigenetics & Nuclear Signalling
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Notes
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Rad51b 1h3/13 detects as little as 10ng of purified protein
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