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Anti-Mycobacterial 30-kDa [A4g4]

Invented by Professor Pranab K Das

Info

Catalogue Number 154074
Applications ELISA IHC WB
Antigen/Gene or Protein Targets Mycobacterial 30-kDa
Reactivity Mycobacterium bovis
Relevance Proteins of the antigen 85 complex in the 30-kDa region secreted by live mycobacteria are important in the immune response against mycobacterial infections and play an important biological role in the host-parasite interaction. This antibody recognises antigen 85B (MPT59) only. This antibody also specifically stained M.leprae bacilli within macrophages in highly bacilliferous lepromatous leprosy lesions.
Host Mouse
Immunogen 30-kDa antigen isolated from M.tuberculosis (RIVM-strain 7114)
Positive Control M.tuberculosis
Subclass IgG1
Myeloma Used P3X63Ag8.653
Recommended Growing Conditions RPMI 1640
Strain Balb/c
Notes Reacts with M.bovis BCG, M.tuberculosis complex and M.leprae. Does not react with E.coli.
Research Area Bacteriology, Immunology, Microbiology

References

There are 4 reference entries for this reagent.

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References: 4 entries

Rambukkana et al. 1993. Infect Immun. 61(5):1835-45. PMID: 7682995.

The mycobacterial secreted antigen 85 complex possesses epitopes that are differentially expressed in human leprosy lesions and Mycobacterium leprae-infected armadillo tissues.

Europe PMC ID: 7682995

Rambukkana et al. 1992. Infect Immun. 60(12):5172-81. PMID: 1280626.

Heterogeneity of monoclonal antibody-reactive epitopes on mycobacterial 30-kilodalton-region proteins and the secreted antigen 85 complex and demonstration of antigen 85B on the Mycobacterium leprae cell wall surface.

Europe PMC ID: 1280626


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References: 4 entries

Rambukkana et al. 1993. Infect Immun. 61(5):1835-45. PMID: 7682995.

The mycobacterial secreted antigen 85 complex possesses epitopes that are differentially expressed in human leprosy lesions and Mycobacterium leprae-infected armadillo tissues.

Rambukkana et al. 1992. Infect Immun. 60(12):5172-81. PMID: 1280626.

Heterogeneity of monoclonal antibody-reactive epitopes on mycobacterial 30-kilodalton-region proteins and the secreted antigen 85 complex and demonstration of antigen 85B on the Mycobacterium leprae cell wall surface.


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Inventor Information

Inventors

Professor Pranab K Das

Professor Pranab K Das

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