Anti-O-GlcNAc (CTD110.6) antibody
Invented at Johns Hopkins University
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 153987 |
| Applications | ELISA IHC IP WB |
| Antigen/Gene or Protein Targets | β-O-linked N-acetylglucosamine (O-GlcNAc) in β-O-glycosidic linkage to both serine and threonine and does not cross react with α-linked Ser/Thr-O-GlcNAc, α-linked Ser-O-linked N-acetylgalactosamine or N-linked oligosaccharides on ovalbumin and immunoglobulin G. |
| Reactivity | Human, Mouse, Primate, Rat and All |
| Relevance | The β-O-linked N-acetylglucosamine (O-GlcNAc) antibody recognizes glycosylation, a post-translational modification, which occurs on serine and threonine residues of proteins in the nuclear and cytoplasmic compartments. This type of glycosylation results in a single moiety and not a complex branched structure. The O-GlcNAc antibody does not cross react with α-linked Ser/Thr-O-GlcNAc, α-linked Ser-O-linked N-acetylgalactosamine or N-linked oligosaccharides on ovalbumin and immunoglobulin G. |
| Host | Mouse |
| Immunogen | Synthetic glycopeptide (YSPTS(O-GlcNAc)PSK) |
| Subclass | IgM |
| Research Area | Cell Signaling & Signal Transduction, Other, Protein Degradation, Structural Biology |
References: 2 entries
Comer et al. 2001. Anal Biochem. 293(2):169-77. PMID: 11399029.
Characterization of a mouse monoclonal antibody specific for O-linked N-acetylglucosamine.
Europe PMC ID: 11399029
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References: 2 entries
Comer et al. 2001. Anal Biochem. 293(2):169-77. PMID: 11399029.
Characterization of a mouse monoclonal antibody specific for O-linked N-acetylglucosamine.
Add a reference
