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Monoclonal Antibodies

Anti-Inhibin α [PO23/32]

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Clone PO 23/32 used to detect binding to inhibin α by ELISA. Molecular weight profiles of Pro-αC and inhibin A in IVF serum as determined by various assays. Samples were fractionated through an immunoaffinity/preparative PAGE/electroelution procedure prior to assay. Horizontal dashed line in the αC IFMA profile refers to the sensitivity of the assay. Source: Robertson et al. 2002. J Clin Endocrinol Metab. 87(2):816-24. PMID: 11836327.
Clone PO 23/32 binding region on αC region of the α subunit. Source: Robertson et al. 2001. Mol Cell Endocrinol. 180(1-2):79-86. PMID: 11451575.
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Catalogue Number 153648
Applications ELISA
Antigen/Gene or Protein Targets Inhibin α
Synonyms Inhibin alpha chain, INHA
Reactivity Human
Relevance Higher levels of inhibin α have been associated with a higher risk of cancer progression and recurrence. Clone PO 23/32 is useful in detecting inhibin α levels in cancer cells.
Host Mouse
Immunogen Synthetic peptide corresponding to epitope region aa109-123 of the αC region of α subunit of inhibin A
Positive Control Testis or Ovary
Subclass IgG2a
Molecular Weight (kDa) 40
Myeloma Used Sp2/0-Ag14
Strain Balb/c
Notes Suggested dilutions for use

ELISA 1-8000 ng/L

Research Areas: Endocrinology;Cancer;Fertility;Cell Biology; Cell Signaling & Signal Transduction
Research Area Cancer, Cell Signaling & Signal Transduction

References

There are 4 reference entries for this reagent.

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References: 4 entries

Robertson et al. 2002. J Clin Endocrinol Metab. 87(2):816-24. PMID: 11836327.

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Characterization of inhibin forms and their measurement by an inhibin alpha-subunit ELISA in serum from postmenopausal women with ovarian cancer.

Europe PMC ID: 11836327

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Robertson et al. 2001. Mol Cell Endocrinol. 180(1-2):79-86. PMID: 11451575.

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Development of an inhibin alpha subunit ELISA with broad specificity.

Europe PMC ID: 11451575

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References: 4 entries

Robertson et al. 2002. J Clin Endocrinol Metab. 87(2):816-24. PMID: 11836327.

View  

Characterization of inhibin forms and their measurement by an inhibin alpha-subunit ELISA in serum from postmenopausal women with ovarian cancer.

View  

Robertson et al. 2001. Mol Cell Endocrinol. 180(1-2):79-86. PMID: 11451575.

View  

Development of an inhibin alpha subunit ELISA with broad specificity.

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