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Anti-HuR [4C8] (ChIP Grade)

Info

Catalogue Number 153520
Applications ChIP ELISA IHC EMSA
Antigen/Gene or Protein Targets HuR
Synonyms ELAV-like protein 1, Human antigen R
Reactivity Human
Relevance ELAV-like protein 1 or HuR (human antigen R) is a protein that in humans is encoded by the ELAVL1 gene. The protein encoded by this gene is a member of the ELAVL protein family. This encoded protein contains 3 RNA-binding domains and binds cis-acting AU-rich elements. It stabilizes mRNAs and thereby regulates gene expression.

A popular technique is to use anti-HuR antibodies to pull out interacting mRNAs and thereby analyse gene expression in a particular tissue. Monoclonal antibody 4C8 was selected by its ability to bind to the HuR/mRNA complex and thus is very useful for EMSA, ChIP and CLIP studies.
Host Mouse
Immunogen HuR peptide
Subclass IgG1
Research Area Gene Expression

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