Anti-CCT beta [PK/8/4/4i/2f]
Invented at The Institute of Cancer Research
- Datasheet
- References (6)
- Inventor Info
Info
| Catalogue Number | 153413 |
| Applications | IHC WB |
| Antigen/Gene or Protein Targets | Mouse CCT2 / CCT Beta |
| Synonyms | CCT2; 99D8.1; CCT-beta; CCTB; PRO1633; TCP-1-beta; TCP1 Beta |
| Reactivity | Bovine, Dog, Hamster, Human, Mouse, Pig, Rat, Rabbit and Sheep |
| Relevance | This gene encodes a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. |
| Host | Rat |
| Immunogen | TCP1 beta peptide conjugated to purified tuberculin protein derivative (PPD) (Mouse) |
| Subclass | IgG2b |
| Molecular Weight (kDa) | 55 |
| Strain | Balb/c |
| Notes | Optimal concentrtion for Immunohistochemistry on formalin-fixed, paraffin-embedded (FFPE) human tissue sections is 10 ug/ml. |
| Research Area | Apoptosis and Programmed Cell Death, Cancer, Cell Cycle, Immunology |
References: 6 entries
Satish et al. 2010. Cell Stress Chaperones. 15(6):819-26. PMID: 20393890.
Cloning and expression of rabbit CCT subunits eta and beta in healing cutaneous wounds.
Europe PMC ID: 20393890
Fislová et al. 2010. J Virol. 84(17):8691-9. PMID: 20573828.
Association of the influenza virus RNA polymerase subunit PB2 with the host chaperonin CCT.
Europe PMC ID: 20573828
Satish et al. 2010. PLoS One. 5(4):e10063. PMID: 20442790.
Chaperonin containing T-complex polypeptide subunit eta (CCT-eta) is a specific regulator of fibroblast motility and contractility.
Europe PMC ID: 20442790
Add a reference
References: 6 entries
Satish et al. 2010. Cell Stress Chaperones. 15(6):819-26. PMID: 20393890.
Cloning and expression of rabbit CCT subunits eta and beta in healing cutaneous wounds.
Fislová et al. 2010. J Virol. 84(17):8691-9. PMID: 20573828.
Association of the influenza virus RNA polymerase subunit PB2 with the host chaperonin CCT.
Satish et al. 2010. PLoS One. 5(4):e10063. PMID: 20442790.
Chaperonin containing T-complex polypeptide subunit eta (CCT-eta) is a specific regulator of fibroblast motility and contractility.
Add a reference
