Cancer Research Technology
Log in Register
Menu

Anti-DMC1 [5B10/2]

Invented by Dr Stephen West at Francis Crick Institute

Info

Catalogue Number 152936
Applications IHC IP WB
Antigen/Gene or Protein Targets hDMC1. Human equivalent of E.Coli recA
Synonyms Disrupted meiotic cDNA 1 homolog, Disrupted meiotic cDNA 1, yeast homolog of, dJ199H16.1, DMC 1, DMC1, DMC1 dosage suppressor of mck1 homolog, DMC1 dosage suppressor of mck1 homolog meiosis specific homologous recombination (yeast), DMC1 homologue
Reactivity Human
Relevance May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks.
Host Mouse
Immunogen Recombinant fusion protein (Human). DMC1 protein (expressed as 6xHis fusion in E. coli and band cut out of gel of insoluble pellet).
Subclass IgG2a
Myeloma Used Sp2/0-Ag14
Strain Balb/c
Research Area DNA Damage and Repair, Epigenetics & Nuclear Signalling

References

There are 2 reference entries for this reagent.

View All References

References: 2 entries

Masson et al. 1999. EMBO J. 18(22):6552-60. PMID: 10562567.

The meiosis-specific recombinase hDmc1 forms ring structures and interacts with hRad51.

Europe PMC ID: 10562567


Add a reference

References: 2 entries

Masson et al. 1999. EMBO J. 18(22):6552-60. PMID: 10562567.

The meiosis-specific recombinase hDmc1 forms ring structures and interacts with hRad51.


Add a reference