Anti-APCDD1L [Z35P1F10*C4]
Invented by Ayham Alnabulsi from Vertebrate Antibodies Limited
Invented at Vertebrate Antibodies Limited
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![Western blotting was performed on Jurkat cell lysate using anti-APCDD1L [Z35P1F10*C4] antibody. A 58kDa protein was detected.](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,q_auto/7de04a3c-9666-4456-9e8d-62068e63a682.png)
![Immunohistochemistry was performed on formalin-fixed paraffin-embedded on primary colorectal cancer tissue using anti-APCDD1L [Z35P1F10*C4]. Cytoplasmic staining was observed.
-Antigen retrieval step was required (microwave 10 min @ 950W in 0.01M sodium citrate buffer, pH 6.0).](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,q_auto/7c6a1f6f-0288-4357-bde4-0e5fa46d9f47.jpg)
![Western blotting was performed on Jurkat cell lysate using anti-APCDD1L [Z35P1F10*C4] antibody. A 58kDa protein was detected.](https://res.cloudinary.com/ximbio/image/upload/c_limit,fl_lossy,h_282,q_auto,w_368/7de04a3c-9666-4456-9e8d-62068e63a682.png)
![Immunohistochemistry was performed on formalin-fixed paraffin-embedded on primary colorectal cancer tissue using anti-APCDD1L [Z35P1F10*C4]. Cytoplasmic staining was observed.
-Antigen retrieval step was required (microwave 10 min @ 950W in 0.01M sodium citrate buffer, pH 6.0).](https://res.cloudinary.com/ximbio/image/upload/c_limit,fl_lossy,h_282,q_auto,w_368/7c6a1f6f-0288-4357-bde4-0e5fa46d9f47.jpg)
![Image thumbnail for Anti-APCDD1L [Z35P1F10*C4]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/7de04a3c-9666-4456-9e8d-62068e63a682.png)
![Image thumbnail for Anti-APCDD1L [Z35P1F10*C4]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/7c6a1f6f-0288-4357-bde4-0e5fa46d9f47.jpg)
| Catalogue Number | 152767 |
| Applications | ELISA IHC WB |
| Antigen/Gene or Protein Targets | Adenomatosis Polyposis Coli Down-Regulated 1-Like (APCDD1L) |
| Synonyms | APCDD1-like, Adenomatosis polyposis coli down-regulated 1 protein-like |
| Reactivity | Human |
| Relevance | Adenomatosis Polyposis Coli Down-Regulated 1-Like (APCDD1L) is a negative regulator of the Wnt signaling pathway. ADCDD1L inhibits Wnt signaling in a cell-autonomous manner and functions upstream of beta-catenin. It is abundantly expressed in human hair follicles and is mutated in heteditary hypotrichosis simplex (HTS). |
| Host | Mouse |
| Immunogen | Peptide Sequence –KRPTSYQA (immunogen peptide is identical in sheep, cow, pig, horse and chicken) |
| Positive Control | Jurkat cell lysate |
| Subclass | IgG |
| Molecular Weight (kDa) | 58 |
| Myeloma Used | P3X63Ag8.653 |
| Strain | Balb/c |
| Research Area | Cell Signaling & Signal Transduction |
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