Anti-ELOVL Fatty Acid Elongase 7 [Z26]
Invented by Ayham Alnabulsi from Vertebrate Antibodies Limited
Invented at Vertebrate Antibodies Limited
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![Western blotting was performed on Jurkat cell lysates using anti-ELOVL Fatty Acid Elongase 7 [Z26]. A 35kDa protein was detected.](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,q_auto/6c7f83a4-4090-4b89-9b35-ea92cdc9b84e.jpg)
![Immunohistochemistry was performed on formalin-fixed, paraffin-embedded skin sections using Anti-ELOVL Fatty Acid Elongase 7 [Z26].Strong cytoplasmic staining was observed.](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,q_auto/66d0b754-dfb1-420f-98f3-7858ffa27720.jpg)
![Immunohistochemistry images show the immunostaining of Anti-ELOVL Fatty Acid Elongase 7 [Z26] in (A) normal colon mucosa, (B) ELOVL7 negative primary colorectal tumour, and (C) ELOVL7 positive primary colorectal tumour. A variation of immunostaining intensity between cases is observed. Localisation of ELOVL7 is cytoplasmic. IHC was performed on formalin-fixed, paraffin-embedded tissue sections. Antigen retrieval step was required (microwave 10 min @ 950W in 0.01M sodium citrate buffer, pH 6.0).](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,q_auto/3140df16-3fbb-49da-a136-aaa09c072baa.png)
![Western blotting was performed on Jurkat cell lysates using anti-ELOVL Fatty Acid Elongase 7 [Z26]. A 35kDa protein was detected.](https://res.cloudinary.com/ximbio/image/upload/c_limit,fl_lossy,h_282,q_auto,w_368/6c7f83a4-4090-4b89-9b35-ea92cdc9b84e.jpg)
![Immunohistochemistry was performed on formalin-fixed, paraffin-embedded skin sections using Anti-ELOVL Fatty Acid Elongase 7 [Z26].Strong cytoplasmic staining was observed.](https://res.cloudinary.com/ximbio/image/upload/c_limit,fl_lossy,h_282,q_auto,w_368/66d0b754-dfb1-420f-98f3-7858ffa27720.jpg)
![Immunohistochemistry images show the immunostaining of Anti-ELOVL Fatty Acid Elongase 7 [Z26] in (A) normal colon mucosa, (B) ELOVL7 negative primary colorectal tumour, and (C) ELOVL7 positive primary colorectal tumour. A variation of immunostaining intensity between cases is observed. Localisation of ELOVL7 is cytoplasmic. IHC was performed on formalin-fixed, paraffin-embedded tissue sections. Antigen retrieval step was required (microwave 10 min @ 950W in 0.01M sodium citrate buffer, pH 6.0).](https://res.cloudinary.com/ximbio/image/upload/c_limit,fl_lossy,h_282,q_auto,w_368/3140df16-3fbb-49da-a136-aaa09c072baa.png)
![Image thumbnail for Anti-ELOVL Fatty Acid Elongase 7 [Z26]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/6c7f83a4-4090-4b89-9b35-ea92cdc9b84e.jpg)
![Image thumbnail for Anti-ELOVL Fatty Acid Elongase 7 [Z26]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/66d0b754-dfb1-420f-98f3-7858ffa27720.jpg)
![Image thumbnail for Anti-ELOVL Fatty Acid Elongase 7 [Z26]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/3140df16-3fbb-49da-a136-aaa09c072baa.png)
| Catalogue Number | 152763 |
| Applications | ELISA IHC WB |
| Antigen/Gene or Protein Targets | ELOVL Fatty Acid Elongase 7 (ELOVL7) |
| Synonyms | Elongation of very long chain fatty acids protein 7, 3-keto acyl-CoA synthase ELOVL7, ELOVL fatty acid elongase 7, ELOVL FA elongase, Very long chain 3-ketoacyl-CoA synthase 7, Very long chain 3-oxoacyl-CoA synthase 7 |
| Reactivity | Human |
| Relevance | ELOVL Fatty Acid Elongase 7 (ELOVL7) is a condensing enzyme that catalyzes the synthesis of saturated and polyunsaturated very long chain fatty acids. Highest activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs. Belongs to the ELO family of proteins which are eukaryotic integral membrane proteins involved in fatty acid elongation. Expressed in most tissues except heart and skeletal muscle. Localised to the endoplasmic reticulum membrane. Biological process keywords: Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism. |
| Host | Mouse |
| Immunogen | Peptide Sequence – RAYTKGQRLP (peptide immunogen is identical in rat (Rattus norvegicus), mouse (Mus musculus), cow (Bos taurus), dog (Canis familiaris), horse (Equus caballus) |
| Positive Control | Jurkat cell lysate |
| Subclass | IgG |
| Molecular Weight (kDa) | 35 |
| Myeloma Used | P3X63Ag8.653 |
| Strain | Balb/c |
| Research Area | Cancer, Cardiovascular, Cell Signaling & Signal Transduction, Metabolism |
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