Anti-cMyc [PM3E7]
Invented at Cancer Research UK London Research Institute: Lincoln's Inn Fields
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 152697 |
| Applications | IHC IP WB |
| Antigen/Gene or Protein Targets | cMyc, c-Myc |
| Reactivity | Human |
| Relevance | The c-Myc and N-Myc oncogenes are members of the Myc family of transcription factors that regulate cell proliferation and apoptosis. c-Myc is expressed in proliferating tissues and increased c-Myc expression is found in many cancers. N-Myc is amplified in a proportion of neuroblastoma patients. |
| Host | Mouse |
| Immunogen | A synthetic peptide APSEDIWKKFEL corresponding to amino acids 44-55 of c-Myc coupled to PPD |
| Subclass | IgG2a |
| Myeloma Used | Sp2/0-Ag14 |
| Recommended Growing Conditions | RPMI 1640 + 10% FCS + 5 x 10*-5 M 2-mercaptoethanol |
| Strain | Balb/c |
| Research Area | Cancer, Cell Cycle, Epigenetics & Nuclear Signalling, Stem Cell Biology |
References: 2 entries
Evan et al. 1988. Curr Top Microbiol Immunol. 141:189-201. PMID: 3063442.
Immunological probes in the analysis of myc protein expression.
Europe PMC ID: 3063442
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References: 2 entries
Evan et al. 1988. Curr Top Microbiol Immunol. 141:189-201. PMID: 3063442.
Immunological probes in the analysis of myc protein expression.
Add a reference
