Anti-Cytochrome P450 4A11 [M25-P2A10]
Invented by Ayham Alnabulsi from Vertebrate Antibodies Limited
Invented at Vertebrate Antibodies Limited
- Datasheet
- References (4)
- Inventor Info
Info
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| Catalogue Number | 152156 |
| Applications | ELISA IHC WB |
| Antigen/Gene or Protein Targets | Cytochrome P450, family 4, subfamily A, polypeptide 11 (CYP4A11) |
| Reactivity | Drosophila, Human, Mouse, Rat and Xenopus laevis |
| Relevance | CYP4A11 is upregulated in primary and metaststic CRC tumours compared to normal colon mucosa. |
| Host | Mouse |
| Immunogen | Peptide Sequence – KNGIHLRLR (amino acids 499 – 507) |
| Positive Control | ELISA- Peptide immunogen; Western Blot- Human liver microsomes; IHC-Human liver |
| Subclass | IgG1 kappa |
| Myeloma Used | P3X63Ag8.653 |
| Recommended Growing Conditions | Dulbecco’s media containing 20% Fetal Bovine serum (DH20) prepared as follows (for final volume of 300ml: 237ml DMEM plus 60 ml Fetal Bovine Serum plus 3ml L-Glutamine). |
| Strain | Balb/c |
| Research Area | Cancer, Cardiovascular, Cell Signaling & Signal Transduction, Metabolism |
References: 4 entries
Alnabulsi et al. 2017. Br J Cancer. :. PMID: 28557975.
The differential expression of omega-3 and omega-6 fatty acid metabolising enzymes in colorectal cancer and its prognostic significance.
Europe PMC ID: 28557975
Alnabulsi et al. 2016. Characterisation of Arachidonic Acid Metabolising Enzymes in Colorectal Cancer J Pathol. 240 Suppl 1:S1-S48. PMID: 27747872
IHC
Nottingham Pathology 2016. 9th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain & Ireland, 28 June - 1 July 2016.
Europe PMC ID: 27747872
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References: 4 entries
Alnabulsi et al. 2017. Br J Cancer. :. PMID: 28557975.
The differential expression of omega-3 and omega-6 fatty acid metabolising enzymes in colorectal cancer and its prognostic significance.
Alnabulsi et al. 2016. Characterisation of Arachidonic Acid Metabolising Enzymes in Colorectal Cancer J Pathol. 240 Suppl 1:S1-S48. PMID: 27747872
IHC
Nottingham Pathology 2016. 9th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain & Ireland, 28 June - 1 July 2016.
Add a reference
