Anti-TRF2, Polyclonal [SWE38]
Invented by Dr Stephen West from Francis Crick Institute
Invented at Cancer Research UK London Research Institute: Clare Hall Laboratories
- Datasheet
- References (4)
- Inventor Info
Info
| Catalogue Number | 151823 |
| Applications | ChIP IF WB |
| Antigen/Gene or Protein Targets | human TRF2 |
| Reactivity | Human |
| Relevance | TRF2 (also known as TERF2), is a component of the telomere nucleoprotein complex. Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and plays a central role in telomere maintenance and protection against end-to-end fusion of chromosomes. |
| Host | Rabbit |
| Immunogen | His tagged full length recombinant TRF2 (from baculovirus) |
| Formulation | Whole serum |
| Notes |
Other specific Research Areas: Meiosis Staining Pattern: IF/ChIP - locates to meiotic and mitotic chromosomes Suggested Dilutions: WB - 1:2000- 1:4000 |
| Positive Control | Hela S1.2.11 |
| Research Area | Cancer, Epigenetics & Nuclear Signalling |
References: 4 entries
Tarsounas et al. 2004. Cell. 117(3):337-47. PMID: 15109494.
Telomere maintenance requires the RAD51D recombination/repair protein.
Europe PMC ID: 15109494
Tarsounas et al. 2003. Oncogene. 22(8):1115-23. PMID: 12606939.
BRCA2-dependent and independent formation of RAD51 nuclear foci.
Europe PMC ID: 12606939
Add a reference
References: 4 entries
Tarsounas et al. 2004. Cell. 117(3):337-47. PMID: 15109494.
Telomere maintenance requires the RAD51D recombination/repair protein.
Tarsounas et al. 2003. Oncogene. 22(8):1115-23. PMID: 12606939.
BRCA2-dependent and independent formation of RAD51 nuclear foci.
Add a reference
