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Catalogue Number 151717
Antigen/Gene or Protein Targets Human WIPI1, GFP
Parental Line HEK293-A
Host Human
Tissue Embryo
Disease Keywords Cancer, neurodegeneration
Model Transgenic
Relevance The HEK293-A GFP-WIPI1 cell line can be used to study autophagy by light microscopy.It is also useful for high throughput microscopy screens. Stable cell line expressing GFP-tagged human WIPI1 in background of HEK293-A cell line
Production Details HEK293-A cells were transfected with GFP-WIPI1 then selcted with G418, and stable, amino acid responsive clones were selected.
Research Area Apoptosis and Programmed Cell Death, Cancer, Cell Signaling & Signal Transduction, Cellular Transport, Drug Discovery & Development, Metabolism
Growth/Phenotype Keywords Autophagy
Recommended Growing Conditions DMEM with 10% FCS
Notes HEK293-A cells were obtained under licence from AdVec
Cellosaurus ID CVCL_5F67

References

There are 2 reference entries for this reagent.

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References: 2 entries

Dooley et al. 2014. Mol Cell. 55(2):238-52. PMID: 24954904.

WIPI2 links LC3 conjugation with PI3P, autophagosome formation, and pathogen clearance by recruiting Atg12-5-16L1.

Europe PMC ID: 24954904


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References: 2 entries

Dooley et al. 2014. Mol Cell. 55(2):238-52. PMID: 24954904.

WIPI2 links LC3 conjugation with PI3P, autophagosome formation, and pathogen clearance by recruiting Atg12-5-16L1.


Add a reference