Cancer Research Technology
Log in Register
Menu

Anti-RAET1E [RAET1E 79/6]

Info

Catalogue Number 151540
Applications ELISA FACS IF IP Fn WB
Antigen/Gene or Protein Targets RAET1E
Reactivity Human
Relevance RAET1E (Retinoic Acid Early Transcript 1E), or ULBP4, is a member of the RAET1 family of major histocompatibility complex (MHC) class I-related genes. RAET1E and RAET1G differ from the other RAET1 proteins by having a type I membrane-spanning sequence at their C termini rather than glycosylphosphatidylinositol anchor sequences. RAET1E is a functional ligand for NKG2D, which causes lymphocyte activation resulting in the secretion of cytokines.
Host Mouse
Immunogen Recombinant protein of human RAET1E protein produced in E.coli with a N terminal 6x His tag
Subclass IgG2a
Positive Control Stable RAET1E cell line
Research Area Immunology

References: 14 entries

McGilvray et al. 2010. Int J Cancer. 127(6):1412-20. PMID: 20054857.

ULBP2 and RAET1E NKG2D ligands are independent predictors of poor prognosis in ovarian cancer patients.

Europe PMC ID: 20054857

Ohashi et al. 2010. J Biol Chem. 285(22):16408-15. PMID: 20304922.

Post-translational modification of the NKG2D ligand RAET1G leads to cell surface expression of a glycosylphosphatidylinositol-linked isoform.

Europe PMC ID: 20304922

Cao et al. 2007. J Biol Chem. 282(26):18922-8. PMID: 17470428.

RAET1E2, a soluble isoform of the UL16-binding protein RAET1E produced by tumor cells, inhibits NKG2D-mediated NK cytotoxicity.

Europe PMC ID: 17470428

Eagle et al. 2006. Hum Immunol. 67(3):159-69. PMID: 16698438.

Regulation of NKG2D ligand gene expression.

Europe PMC ID: 16698438

Bacon et al. 2004. J Immunol. 173(2):1078-84. PMID: 15240696.

Two human ULBP/RAET1 molecules with transmembrane regions are ligands for NKG2D.

Europe PMC ID: 15240696

Chalupny et al. 2003. Biochem Biophys Res Commun. 305(1):129-35. PMID: 12732206.

ULBP4 is a novel ligand for human NKG2D.

Europe PMC ID: 12732206

Radosavljevic et al. 2002. Genomics. 79(1):114-23. PMID: 11827464.

A cluster of ten novel MHC class I related genes on human chromosome 6q24.2-q25.3.

Europe PMC ID: 11827464


Add a reference

References: 14 entries

McGilvray et al. 2010. Int J Cancer. 127(6):1412-20. PMID: 20054857.

ULBP2 and RAET1E NKG2D ligands are independent predictors of poor prognosis in ovarian cancer patients.

Europe PMC ID: 20054857

Ohashi et al. 2010. J Biol Chem. 285(22):16408-15. PMID: 20304922.

Post-translational modification of the NKG2D ligand RAET1G leads to cell surface expression of a glycosylphosphatidylinositol-linked isoform.

Europe PMC ID: 20304922

Cao et al. 2007. J Biol Chem. 282(26):18922-8. PMID: 17470428.

RAET1E2, a soluble isoform of the UL16-binding protein RAET1E produced by tumor cells, inhibits NKG2D-mediated NK cytotoxicity.

Europe PMC ID: 17470428

Eagle et al. 2006. Hum Immunol. 67(3):159-69. PMID: 16698438.

Regulation of NKG2D ligand gene expression.

Europe PMC ID: 16698438

Bacon et al. 2004. J Immunol. 173(2):1078-84. PMID: 15240696.

Two human ULBP/RAET1 molecules with transmembrane regions are ligands for NKG2D.

Europe PMC ID: 15240696

Chalupny et al. 2003. Biochem Biophys Res Commun. 305(1):129-35. PMID: 12732206.

ULBP4 is a novel ligand for human NKG2D.

Europe PMC ID: 12732206

Radosavljevic et al. 2002. Genomics. 79(1):114-23. PMID: 11827464.

A cluster of ten novel MHC class I related genes on human chromosome 6q24.2-q25.3.

Europe PMC ID: 11827464


Add a reference

References: 14 entries

McGilvray et al. 2010. Int J Cancer. 127(6):1412-20. PMID: 20054857.

ULBP2 and RAET1E NKG2D ligands are independent predictors of poor prognosis in ovarian cancer patients.

Ohashi et al. 2010. J Biol Chem. 285(22):16408-15. PMID: 20304922.

Post-translational modification of the NKG2D ligand RAET1G leads to cell surface expression of a glycosylphosphatidylinositol-linked isoform.

Cao et al. 2007. J Biol Chem. 282(26):18922-8. PMID: 17470428.

RAET1E2, a soluble isoform of the UL16-binding protein RAET1E produced by tumor cells, inhibits NKG2D-mediated NK cytotoxicity.

Eagle et al. 2006. Hum Immunol. 67(3):159-69. PMID: 16698438.

Regulation of NKG2D ligand gene expression.

Bacon et al. 2004. J Immunol. 173(2):1078-84. PMID: 15240696.

Two human ULBP/RAET1 molecules with transmembrane regions are ligands for NKG2D.

Chalupny et al. 2003. Biochem Biophys Res Commun. 305(1):129-35. PMID: 12732206.

ULBP4 is a novel ligand for human NKG2D.

Radosavljevic et al. 2002. Genomics. 79(1):114-23. PMID: 11827464.

A cluster of ten novel MHC class I related genes on human chromosome 6q24.2-q25.3.


Add a reference


This reagent does not have any reviews at the moment.