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Anti-Factor VII [RFF-VII/1]

Info

Catalogue Number 151533
Applications ELISA Fn WB
Antigen/Gene or Protein Targets Factor VII
Reactivity Human
Relevance Factor VII is a 50kDa multi-domain, single chain plasma glycoprotein synthesised in the liver. It is essential for blood coagulation. Factor VII is converted to the active, two chain, serine protease Factor VIIa via cleavage by thrombin, factor Xa, factor IXa or factor XIIa. Factor VIIa converts factor X to factor Xa, which in turn converts prothrombin to thrombin. This monoclonal antibody partially inhibits human Factor VII activity.
Host Mouse
Immunogen Purified human factor VII
Subclass IgG1 kappa
Myeloma Used P3/NS1/1-Ag4.1
Recommended Growing Conditions RPMI + 10% FCS; non-adherent; subculture every 2-3 days; split 1:5
Research Area Cardiovascular

References: 2 entries

Takase et al. 1988. J Clin Pathol. 41(3):342-5. PMID: 3360958.

Takase et al. 1988. J Clin Pathol. 41(3):337-41. PMID: 3360957.


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