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Anti-Melphalan-modified DNA [MP5/73]

Info

Catalogue Number 151466
Applications ELISA IHC
Antigen/Gene or Protein Targets Melphalan
Reactivity N/A
Relevance This antibody was developed to improve detection of melphalan-DNA adducts through its ability to recognise the stabilised adduct. This antibody can be used for quantification of melphalan adducts in purified DNA by ELISA and for immunofluorescent detection of melphalan-DNA adducts in single cells.
Host Rat
Immunogen Native DNA reacted with melphalan
Subclass IgG2b
Positive Control RNA/DNA
Myeloma Used Y3.AG.1.2.3
Recommended Growing Conditions DMEM + 10%FCS + Glu + Pen/Strep
Research Area Cancer

References: 9 entries

Gould et al. 2004. Mol Pharmacol. 66(5):1301-9. PMID: 15308759.

Rothbarth et al. 2004. Biochem Pharmacol. 67(9):1771-8. PMID: 15081876.

Frank et al. 2003. Exp Cell Res. 283(2):127-34. PMID: 12581733.

McCartney et al. 2001. Chem Res Toxicol. 14(1):71-81. PMID: 11170510.

Tilby et al. 1998. Chem Res Toxicol. 11(10):1162-8. PMID: 9778312.

Frank et al. 1996. Blood. 88(3):977-84. PMID: 8704257.

Tilby et al. 1993. Eur J Cancer. 29A(5):681-6. PMID: 8471325.

Tilby et al. 1990. Chem Biol Interact. 73(2-3):183-94. PMID: 2155711.

Tilby et al. 1987. Cancer Res. 47(6):1542-6. PMID: 3815354.


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