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Anti-Cisplatin modified DNA [CP9/19]


Catalogue Number 151464
Antigen/Gene or Protein Targets Cisplatin modified native DNA
Reactivity N/A
Relevance This antibody enables the quantification of cisplatin-induced adducts on DNA. This antibody has also been recently used for isolation of DNA fragments carrying adducts to enhance the sensitivity of subsequent PCR-based analyses and is central to ongoing studies of variation in the nature of cisplatin adducts formed in different cell lines.
Antibody CP9/19 recognises only the intra-strand cross-links formed by cisplatin between adjacent purines.
Host Rat
Immunogen Cisplatin modified native DNA
Subclass IgG2a
Positive Control RNA/DNA
Myeloma Used Y3.AG.1.2.3
Recommended Growing Conditions DMEM + 10%FCS + Glu + Pen/Strep
Notes Alternative Name: ICR4
Research Area DNA Damage and Repair, Epigenetics & Nuclear Signalling

References: 14 entries

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