Anti-ATMIN [ATMIN 11F4]
Invented at Cancer Research UK London Research Institute: Lincoln's Inn Fields
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 151460 |
| Applications | IF IP WB |
| Antigen/Gene or Protein Targets | Ataxia Telangiectasia Mutated Interacting protein (ATMIN, ASCIZ) |
| Reactivity | Human |
| Relevance | The checkpoint kinase ATM (ataxia telangiectasia mutated) transduces genomic stress signals to halt cell cycle progression and promote DNA repair in response to DNA damage. ATMIN (ATM INteracting protein) is an essential cofactor for ATM. ATMIN interacts with ATM through a C-terminal motif, which is also present in Nijmegen breakage syndrome (NBS) 1. |
| Host | Mouse |
| Immunogen | Synthetic peptide |
| Positive Control | 293T Cells |
| Subclass | IgG2a |
| Myeloma Used | Sp2/0-Ag14 |
| Recommended Growing Conditions | E4 + 5% FCS |
| Research Area | DNA Damage and Repair, Epigenetics & Nuclear Signalling |
References: 2 entries
Kanu et al. 2007. EMBO J. 26(12):2933-41. PMID: 17525732.
ATMIN defines an NBS1-independent pathway of ATM signalling.
Europe PMC ID: 17525732
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References: 2 entries
Kanu et al. 2007. EMBO J. 26(12):2933-41. PMID: 17525732.
ATMIN defines an NBS1-independent pathway of ATM signalling.
Add a reference
