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Anti-PCNA [5E6/2]

Info

Catalogue Number 151456
Applications ELISA IP WB
Antigen/Gene or Protein Targets Proliferating cell nuclear antigen, (PCNA), also known as cyclin or polymerase delta accessory protein.
Reactivity Saccharomyces cerevisiae
Relevance The antibody recognises endogenous PCNA protein from budding yeast, Sacchoromyces cerevisiae. PCNA is the replicative clamp protein, an essential processivity factor for DNA polymerases and an interaction partner for many other proteins. By means of its interactions, PCNA coordinates various transactions at the replication fork, ranging from DNA replication and repair to chromatin assembly.
Host Mouse
Immunogen Purified recombinant His6-POL30 (PCNA) from budding yest, Saccharomyces cerevisiae, produced in Escherichia coli
Subclass IgG1
Positive Control Wild type budding yeast expressing native POL30 (PCNA)
Molecular Weight (kDa) 30
Myeloma Used Sp2/0-Ag14
Recommended Growing Conditions RPMI + 5% FCS
Strain CD1
Research Area Cancer, Cell Cycle, Cell Type or Organelle Marker, Epigenetics & Nuclear Signalling

References: 8 entries

Kubota et al. 2011. Mol Cell Proteomics. 10(7):M110.005561. PMID: 21505101.

Quantitative proteomic analysis of chromatin reveals that Ctf18 acts in the DNA replication checkpoint.

Europe PMC ID: 21505101

Parker et al. 2008. EMBO J. 27(18):2422-31. PMID: 18701921.

SUMO modification of PCNA is controlled by DNA.

Europe PMC ID: 18701921

Davies et al. 2008. Mol Cell. 29(5):625-36. PMID: 18342608.

Activation of ubiquitin-dependent DNA damage bypass is mediated by replication protein a.

Europe PMC ID: 18342608

Windecker et al. 2008. J Mol Biol. 376(1):221-31. PMID: 18155241.

Architecture and assembly of poly-SUMO chains on PCNA in Saccharomyces cerevisiae.

Europe PMC ID: 18155241


Add a reference

References: 8 entries

Kubota et al. 2011. Mol Cell Proteomics. 10(7):M110.005561. PMID: 21505101.

Quantitative proteomic analysis of chromatin reveals that Ctf18 acts in the DNA replication checkpoint.

Europe PMC ID: 21505101

Parker et al. 2008. EMBO J. 27(18):2422-31. PMID: 18701921.

SUMO modification of PCNA is controlled by DNA.

Europe PMC ID: 18701921

Davies et al. 2008. Mol Cell. 29(5):625-36. PMID: 18342608.

Activation of ubiquitin-dependent DNA damage bypass is mediated by replication protein a.

Europe PMC ID: 18342608

Windecker et al. 2008. J Mol Biol. 376(1):221-31. PMID: 18155241.

Architecture and assembly of poly-SUMO chains on PCNA in Saccharomyces cerevisiae.

Europe PMC ID: 18155241


Add a reference

References: 8 entries

Kubota et al. 2011. Mol Cell Proteomics. 10(7):M110.005561. PMID: 21505101.

Quantitative proteomic analysis of chromatin reveals that Ctf18 acts in the DNA replication checkpoint.

Parker et al. 2008. EMBO J. 27(18):2422-31. PMID: 18701921.

SUMO modification of PCNA is controlled by DNA.

Davies et al. 2008. Mol Cell. 29(5):625-36. PMID: 18342608.

Activation of ubiquitin-dependent DNA damage bypass is mediated by replication protein a.

Windecker et al. 2008. J Mol Biol. 376(1):221-31. PMID: 18155241.

Architecture and assembly of poly-SUMO chains on PCNA in Saccharomyces cerevisiae.


Add a reference


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