Anti-HLADR [CR3/43]
Invented by Dr Jacqueline Cordell at University of Oxford
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| Catalogue Number | 151383 |
| Applications | FACS IHC WB |
| Antigen/Gene or Protein Targets | Human Leukocyte Antigen DR (MHC class II) |
| Reactivity | Human |
| Relevance | Human Leukocyte Antigens (HLA) are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D). CR3/43 may be used for HLA typing. |
| Host | Mouse |
| Immunogen | Tonsil cells |
| Subclass | IgG1 |
| Myeloma Used | P3/NS1/1-Ag4.1 |
| Recommended Growing Conditions | RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT |
| Notes | Ultroser G can be used at 1% if the cells are not growing well. |
| Research Area | Immunology |
References: 6 entries
Breshears et al. 2012. J Biol Chem. 287(39):32578-87. PMID: 22833676.
A disintegrin and metalloproteinase 17 (ADAM17) and epidermal growth factor receptor (EGFR) signaling drive the epithelial response to Staphylococcus aureus toxic shock syndrome toxin-1 (TSST-1).
Europe PMC ID: 22833676
Gatter et al. 1982. Semin Oncol. 9(4):517-25. PMID: 6189189.
The use of monoclonal antibodies for histopathologic diagnosis of human malignancy.
Europe PMC ID: 6189189
Gatter et al. 1982. J Clin Pathol. 35(11):1253-67. PMID: 6183295.
Use of monoclonal antibodies for the histopathological diagnosis of human malignancy.
Europe PMC ID: 6183295
Add a reference
References: 6 entries
Breshears et al. 2012. J Biol Chem. 287(39):32578-87. PMID: 22833676.
A disintegrin and metalloproteinase 17 (ADAM17) and epidermal growth factor receptor (EGFR) signaling drive the epithelial response to Staphylococcus aureus toxic shock syndrome toxin-1 (TSST-1).
Europe PMC ID: 22833676
Gatter et al. 1982. Semin Oncol. 9(4):517-25. PMID: 6189189.
The use of monoclonal antibodies for histopathologic diagnosis of human malignancy.
Europe PMC ID: 6189189
Gatter et al. 1982. J Clin Pathol. 35(11):1253-67. PMID: 6183295.
Use of monoclonal antibodies for the histopathological diagnosis of human malignancy.
Europe PMC ID: 6183295
Add a reference
References: 6 entries
Breshears et al. 2012. J Biol Chem. 287(39):32578-87. PMID: 22833676.
A disintegrin and metalloproteinase 17 (ADAM17) and epidermal growth factor receptor (EGFR) signaling drive the epithelial response to Staphylococcus aureus toxic shock syndrome toxin-1 (TSST-1).
Gatter et al. 1982. Semin Oncol. 9(4):517-25. PMID: 6189189.
The use of monoclonal antibodies for histopathologic diagnosis of human malignancy.
Gatter et al. 1982. J Clin Pathol. 35(11):1253-67. PMID: 6183295.
Use of monoclonal antibodies for the histopathological diagnosis of human malignancy.
Add a reference
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