Anti-Haemoglobin Scavenger Receptor [GHI/61]
Invented by Karen Pulford at University of Oxford
- Datasheet
- References (10)
- Inventor Info
Info
| Catalogue Number | 151380 |
| Applications | FACS IHC IF IP Fn WB |
| Antigen/Gene or Protein Targets | Haemoglobin Scavenger Receptor (M130; CD163) |
| Reactivity | Human |
| Relevance | The Haemoglobin Scavenger Receptor is a membrane glycoprotein of 130 kDa. It is expressed exclusively on the cell surface of human monocytes and macrophages that evolve predominantly in the late phase of inflammation. This receptor is a member of the scavenger receptor cysteine-rich superfamily, it is a receptor for the haemoglobin-haptoglobin complex |
| Host | Mouse |
| Immunogen | Hairy cell leukaemia cells |
| Subclass | IgG1 |
| Myeloma Used | P3/NS1/1-Ag4.1 |
| Recommended Growing Conditions | RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT |
| Notes | Ultroser G can be used at 1% if the cells are not growing well. |
| Research Area | Cardiovascular, Immunology |
References: 10 entries
Moura et al. 2012. Eur J Immunol. 42(11):2925-36. PMID: 22851198.
CD163 favors Mycobacterium leprae survival and persistence by promoting anti-inflammatory pathways in lepromatous macrophages.
Europe PMC ID: 22851198
Moniuszko et al. 2006. Clin Vaccine Immunol. 13(6):704-7. PMID: 16760331.
Monocyte CD163 and CD36 expression in human whole blood and isolated mononuclear cell samples: influence of different anticoagulants.
Europe PMC ID: 16760331
Møller et al. 2002. Blood. 99(1):378-80. PMID: 11756196.
Identification of the hemoglobin scavenger receptor/CD163 as a natural soluble protein in plasma.
Europe PMC ID: 11756196
Law et al. 1993. Eur J Immunol. 23(9):2320-5. PMID: 8370408.
A new macrophage differentiation antigen which is a member of the scavenger receptor superfamily.
Europe PMC ID: 8370408
Pulford et al. 1992. Immunology. 75(4):588-95. PMID: 1592433.
A monocyte/macrophage antigen recognized by the four antibodies GHI/61, Ber-MAC3, Ki-M8 and SM4.
Europe PMC ID: 1592433
Add a reference
References: 10 entries
Moura et al. 2012. Eur J Immunol. 42(11):2925-36. PMID: 22851198.
CD163 favors Mycobacterium leprae survival and persistence by promoting anti-inflammatory pathways in lepromatous macrophages.
Moniuszko et al. 2006. Clin Vaccine Immunol. 13(6):704-7. PMID: 16760331.
Monocyte CD163 and CD36 expression in human whole blood and isolated mononuclear cell samples: influence of different anticoagulants.
Møller et al. 2002. Blood. 99(1):378-80. PMID: 11756196.
Identification of the hemoglobin scavenger receptor/CD163 as a natural soluble protein in plasma.
Law et al. 1993. Eur J Immunol. 23(9):2320-5. PMID: 8370408.
A new macrophage differentiation antigen which is a member of the scavenger receptor superfamily.
Pulford et al. 1992. Immunology. 75(4):588-95. PMID: 1592433.
A monocyte/macrophage antigen recognized by the four antibodies GHI/61, Ber-MAC3, Ki-M8 and SM4.
Add a reference
