Anti-Integrin b3 [Y2/51]
Invented by Dr Jacqueline Cordell at University of Oxford
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| Catalogue Number | 151367 |
| Applications | FACS IHC IF WB |
| Antigen/Gene or Protein Targets | Integrin ß3 (CD61; GPIIIa) |
| Synonyms | Integrin Subunit Beta; Integrin; Beta 3 (Platelet Glycoprotein IIIa; Antigen CD61); Platelet Membrane Glycoprotein IIIa; Antigen CD61; GPIIIa; GP3A; Platelet Glycoprotein IIIa; Integrin Beta 3; CD61 Antigen; BDPLT16; BDPLT2; CD61; GT |
| Reactivity | Human |
| Relevance | CD61 is expressed by megakaryocytes, platelets and osteoclasts. Y2/51 is widely used as a marker of megakaryocytes in bone marrow trephines. |
| Host | Mouse |
| Immunogen | Phytohaemagglutin-stimulated peripheral blood cells |
| Subclass | IgG1 |
| Myeloma Used | P3/NS1/1-Ag4.1 |
| Recommended Growing Conditions | RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT |
| Notes | Ultroser G can be used at 1% if the cells are not growing well. |
| Research Area | Adhesion, Cardiovascular, Cell Signaling & Signal Transduction |
References: 8 entries
Brune et al. 2007. Eur Cell Mater. 14:78-90; discussion 90-1. PMID: 18085506.
In vitro comparison of human fibroblasts from intact and ruptured ACL for use in tissue engineering.
Europe PMC ID: 18085506
Gatter et al. 1988. Histopathology. 13(3):257-67. PMID: 3192191.
The immunohistological detection of platelets, megakaryocytes and thrombi in routinely processed specimens.
Europe PMC ID: 3192191
Vinci et al. 1984. Br J Haematol. 56(4):589-605. PMID: 6231944.
Immunological study of in vitro maturation of human megakaryocytes.
Europe PMC ID: 6231944
Nachman et al. 1982. J Clin Invest. 69(2):263-9. PMID: 6460044.
Complex formation of platelet membrane glycoproteins IIb and IIIa with fibrinogen.
Europe PMC ID: 6460044
Add a reference
References: 8 entries
Brune et al. 2007. Eur Cell Mater. 14:78-90; discussion 90-1. PMID: 18085506.
In vitro comparison of human fibroblasts from intact and ruptured ACL for use in tissue engineering.
Europe PMC ID: 18085506
Gatter et al. 1988. Histopathology. 13(3):257-67. PMID: 3192191.
The immunohistological detection of platelets, megakaryocytes and thrombi in routinely processed specimens.
Europe PMC ID: 3192191
Vinci et al. 1984. Br J Haematol. 56(4):589-605. PMID: 6231944.
Immunological study of in vitro maturation of human megakaryocytes.
Europe PMC ID: 6231944
Nachman et al. 1982. J Clin Invest. 69(2):263-9. PMID: 6460044.
Complex formation of platelet membrane glycoproteins IIb and IIIa with fibrinogen.
Europe PMC ID: 6460044
Add a reference
References: 8 entries
Brune et al. 2007. Eur Cell Mater. 14:78-90; discussion 90-1. PMID: 18085506.
In vitro comparison of human fibroblasts from intact and ruptured ACL for use in tissue engineering.
Gatter et al. 1988. Histopathology. 13(3):257-67. PMID: 3192191.
The immunohistological detection of platelets, megakaryocytes and thrombi in routinely processed specimens.
Vinci et al. 1984. Br J Haematol. 56(4):589-605. PMID: 6231944.
Immunological study of in vitro maturation of human megakaryocytes.
Nachman et al. 1982. J Clin Invest. 69(2):263-9. PMID: 6460044.
Complex formation of platelet membrane glycoproteins IIb and IIIa with fibrinogen.
Add a reference
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