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Anti-Integrin b3 [Y2/51]


Catalogue Number 151367
Applications FACS IHC IF WB
Antigen/Gene or Protein Targets Integrin ß3 (CD61; GPIIIa)
Synonyms Integrin Subunit Beta; Integrin; Beta 3 (Platelet Glycoprotein IIIa; Antigen CD61); Platelet Membrane Glycoprotein IIIa; Antigen CD61; GPIIIa; GP3A; Platelet Glycoprotein IIIa; Integrin Beta 3; CD61 Antigen; BDPLT16; BDPLT2; CD61; GT
Reactivity Human
Relevance CD61 is expressed by megakaryocytes, platelets and osteoclasts. Y2/51 is widely used as a marker of megakaryocytes in bone marrow trephines.
Host Mouse
Immunogen Phytohaemagglutin-stimulated peripheral blood cells
Subclass IgG1
Myeloma Used P3/NS1/1-Ag4.1
Recommended Growing Conditions RPMI 1640 + 10% FCS + penicillin (100U/ml) + streptomycin (100mg/l) + glutamine (2mM) + HAT
Notes Ultroser G can be used at 1% if the cells are not growing well.
Research Area Adhesion, Cardiovascular, Cell Signaling & Signal Transduction

References: 4 entries

Brune et al. 2007. Eur Cell Mater. 14:78-90; discussion 90-1. PMID: 18085506.

Gatter et al. 1988. Histopathology. 13(3):257-67. PMID: 3192191.

Vinci et al. 1984. Br J Haematol. 56(4):589-605. PMID: 6231944.

Nachman et al. 1982. J Clin Invest. 69(2):263-9. PMID: 6460044.

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